Associations between coronary artery disease, aneurysm and ectasia.
Associations between coronary artery disease, aneurysm and ectasia.
复制标题
DOI：
10.5114/kitp.2017.70276
复制
发表时间：
2017-09
期刊：
影响因子：
--
通讯作者：
Morrad B
中科院分区：
文献类型：
--
作者：
Ovalı C;Morrad B
研究冠状动脉瘤/扩张的频率和贡献以及其与冠状动脉疾病（CAD）的相关性。我们回顾性评估了6500名成人连续患者的冠状动脉造影记录，其中418名符合纳入标准并用于本研究。CAD定义为至少一条心外膜冠状动脉存在血管造影冠状动脉狭窄，狭窄程度大于管腔直径的50%。比较冠心病组与非冠心病组冠状动脉瘤/扩张的发生率及特点。我们在6.6%的显著CAD（+）患者和6.1%的显著CAD（-）患者中观察到冠状动脉瘤（CAA）和扩张（CAE）（p = 0.2）。CAD（+）患者的冠状动脉瘤百分比显著高于CAD（-）患者（0.8% vs. 0.4%，p = 0.015）。CAD（+）患者和CAD（-）患者的冠状动脉扩张百分比无差异（5.8% vs. 5.7%，p = 0.47）。发现单一冠状动脉上的动脉瘤的频率高于识别两个或三个冠状动脉上的动脉瘤。在接受血管造影术的患者中，经常会遇到CAA或CAE病例。此外，CAA和CAE不应被认为是简单的血管扩张。对CAA或CAE患者的有效治疗和预后评估还需进一步研究。
Investigation the frequency and contribution of coronary artery aneurysm/ectasia in addition to their correlation with coronary artery disease (CAD). We retrospectively evaluated the coronary angiography records of 6500 adult consecutive patients, and 418 of them were met inclusion criteria and used in the present study. The CAD was defined as the presence of angiographic coronary stenosis of > 50% of the luminal diameter in no less than one of the epicardial coronary arteries. Moreover, the prevalence and features of the coronary artery aneurysm/ectasia among the cases with and without CAD were compared. We observed coronary artery aneurysm (CAA) and ectasia (CAE) in 6.6% of the patients with significant CAD (+), and 6.1% of the patients with significant CAD (–) (p = 0.2). The percentage of coronary artery aneurysms was significantly higher in CAD (+) patients than in CAD (–) patients (0.8% vs. 0.4%, p = 0.015). The percentage of coronary artery ectasia showed no variation between CAD (+) patients and CAD (–) patients (5.8% vs. 5.7%, p = 0.47). The frequency of spotting aneurysm on a single coronary artery was higher than discerning aneurysm on two or three coronary arteries. Presence of CAA or CAE cases is often encountered in those who have undergone angiography procedures. Furthermore, CAA and CAE should not be considered as simple dilations of vessels. Further studies are needed to determine the effective procedures for the treatment and prognostic evaluations of the patients with CAA or CAE.