Lumbar spine bone mineral density in US adults: demographic patterns and relationship with femur neck skeletal status
Lumbar spine bone mineral density in US adults: demographic patterns and relationship with femur neck skeletal status
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DOI：
10.1007/s00198-011-1693-z
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发表时间：
2012-04-01
影响因子：
4
通讯作者：
Shepherd, J. A.
中科院分区：
文献类型：
--
作者：
Looker, A. C.;Melton, L. J., III;Shepherd, J. A.
本分析按年龄、性别和人种/种族检查了2005-2008年NHANES中美国成年人的腰椎骨密度（BMD）。我们还评估了老年人脊柱和股骨颈低BMD的患病率和患病率之间的一致性。来自美国人口代表性样本的腰椎BMD数据以前没有。我们使用了2005年全国健康和营养调查的数据，2008年，研究了美国成年人腰椎BMD的人口统计学模式，年龄为千分之20岁，以及成年人腰椎BMD低的患病率为千分之50岁。还评估了老年人股骨颈和脊柱低BMD患病率之间的一致性。采用双能X线骨密度仪测量腰椎和股骨颈骨密度。与非西班牙裔白人相比，非西班牙裔黑人的腰椎BMD较高，墨西哥裔美国人的腰椎BMD较低。女性腰椎BMD随年龄增长而下降，男性则无此现象。2005-2008年，约470万（10%）美国老年女性和100万（3%）老年男性患有腰椎骨质疏松症。大约三分之一的人在脊柱和髋关节的骨骼状态不同，但大多数人在一个部位正常，在另一个部位骨质减少。根据性别，只有3- 10%的人在一个骨骼部位患有骨质疏松症，而在另一个骨骼部位则没有。76%~ 87%的骨骼状态不一致的患者腰椎T评分在1个单位的分类阈值内，这些结果表明，测量股骨颈或腰椎将正确地将大多数接受治疗的患者分类为腰椎病或非腰椎病。
This analysis examines lumbar spine bone mineral density (BMD) of US adults from NHANES 2005-2008 by age, sex, and race/ethnicity. Prevalence of low spine BMD and agreement between the prevalence of low BMD at the spine and femur neck in older adults are also assessed.Lumbar spine BMD data from a representative sample of the US population have not been previously available.We used data from the National Health and Nutrition Examination Survey 2005-2008 to examine demographic patterns in lumbar spine BMD among US adults age a parts per thousand yen20 years and the prevalence of low lumbar spine BMD in adults age a parts per thousand yen50 years. Agreement between the prevalence of low BMD at the femur neck and spine in older adults was also assessed. Dual-energy X-ray absorptiometry was used to measure lumbar spine and femur neck BMD. World Health Organization definitions were used to categorize skeletal status as normal, osteopenia, or osteoporosis.Compared to non-Hispanic whites, non-Hispanic blacks had higher and Mexican Americans had lower lumbar spine BMD. Lumbar spine BMD declined with age in women, but not in men. Approximately 4.7 million (10%) older US women and 1 million (3%) older men had lumbar spine osteoporosis in 2005-2008. Roughly one third of them differed in skeletal status at the spine and hip but most were normal at one site and osteopenic at the other. Only 3-10%, depending on sex, had osteoporosis at one skeletal site but not at the other skeletal site. Between 76% and 87% with discordant skeletal status had lumbar spine T-scores within 1 unit of the category threshold.These findings suggest that measuring either the femur neck or the lumbar spine will correctly classify the majority of individuals who present for care as osteoporotic or not.