Rapid diagnostic test for ocular adenovirus.
Rapid diagnostic test for ocular adenovirus.
复制标题
眼腺病毒快速诊断检测。
DOI：
10.1016/s0161-6420(88)33168-4
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发表时间：
1988
期刊：
影响因子：
13.7
通讯作者：
Gordon,YJ
中科院分区：
文献类型：
--
作者：
Wiley,L;Springer,D;Kowalski,RP;Arffa,R;Roat,MI;Thoft,RA;Gordon,YJ
评价了一种新的直接酶免疫测定试验（Adenoclone，剑桥Bioscience，Hopkinton，MA）用于快速诊断眼部腺病毒感染。在36例培养证实的腺病毒眼部感染病例中，在症状发作1周内检测的31例患者中有24例（77%）结膜拭子直接腺克隆试验阳性，在1周后出现的5例患者中有1例（20%）阳性（P< 0.02）。总体敏感性为69%，而特异性为100%。作者得出结论，阳性腺病毒试验在早期腺病毒眼部感染的快速诊断中是可靠的。
A new, direct, enzyme immunoassay test (Adenoclone, Cambridge BioScience, Hopkinton, MA) was evaluated for the rapid diagnosis of ocular adenovirus infections. In 36 culture-proven cases of adenovirus ocular infection, direct Adenoclone testing of conjunctival swabs was positive in 24 of 31 patients (77%) tested within 1 week of onset of symptoms, and in one of five patients (20%) who presented after 1 week (P< 0.02). Overall sensitivity was 69%, whereas specificity was 100%. The authors conclude that a positive Adenoclone test is reliable in the rapid diagnosis of early adenovirus ocular infections.