Tumor-derived exosomes:: a new source of tumor rejection antigens
Tumor-derived exosomes:: a new source of tumor rejection antigens
复制标题
DOI:
10.1016/s0264-410x(02)00384-5
复制
发表时间:
2002-12-19
期刊:
影响因子:
5.5
通讯作者:
Zitvogel, L
中科院分区:
文献类型:
--
作者:
André, F;Scharz, NEC;Zitvogel, L
Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells induce immune-mediated anti-tumor response in mice. Here, we will describe the biochemical properties of tumor-derived exosomes and, their pre-clinical activity as cancer vaccines. (C) 2002 Elsevier Science Ltd. All rights reserved.