Near-infrared images using continuous, phase-modulated, and pulsed light with quantitation of blood and blood oxygenation
Near-infrared images using continuous, phase-modulated, and pulsed light with quantitation of blood and blood oxygenation
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DOI：
10.1111/j.1749-6632.1998.tb08185.x
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发表时间：
1998-01-01
期刊：
影响因子：
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通讯作者：
Chance, B
中科院分区：
文献类型：
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作者：
Chance, B
我的目的是强调光学断层扫描可以用一种安全简单的技术填补乳腺癌检测的空白。图1显示了这个小生境，其中BRCA-1基因缺陷的统计数据显示，在40岁时，携带BRCA-1突变体的女性患癌症的概率与我所达到的舒适年龄的正常女性相同。“因此，如果一个人处于40岁以下人群的利基，X射线乳房X光检查的方式可能会产生危险的终生累积剂量，并且由于硬压缩而有点不适，以获得更好的X射线图像。此外，乳房X光片被乳房中的胶原纤维变成白色，也无法检测出癌症。40岁以下的BRCA-1人群存在严重的诊断问题。
My purpose is to emphasize the niche that optical tomography could fill in breast cancer detection with a safe and simple technique. This niche is shown in FicURE 1, where the statistics of the gene defect, BRCA-1, show that at the age of 40, a woman carrying the BRCA-1 mutant would have the same probability of cancer as a normal woman at the comfortable age that I have achieved." So if a person is in the niche of the under-40 group, the modality of X-ray mammography may give a dangerous lifetime accumulated dosage as well as be somewhat discomforting due to hard compression to get better X-ray images. In addition, the mammogram is turned white by the collagen fibers in the breast, and it is not possible to detect cancer. The under-40-year-old BRCA-1 population have a serious diagnos-tic problem.