Supportive medications and interventions received by prostate cancer survivors: results from the PiCTure study
Supportive medications and interventions received by prostate cancer survivors: results from the PiCTure study
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前列腺癌幸存者接受的支持性药物和干预措施：PiCture 研究的结果
DOI：
10.12788/jcso.0384
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
L. Sharp
中科院分区：
文献类型：
--
作者：
F. Drummond;A. Gavin;L. Sharp
前列腺癌的治疗与各种生理后遗症有关，包括泌尿系症状、性症状和肠道症状。1术后可对幸存者的健康相关生活质量产生影响。2已有药物和外科干预措施可用于管理或改善许多这些后遗症(例如，放疗期间和放疗后服用西地那和L柠檬酸盐可改善性功能)，3并且接受治疗对患者的性功能有积极影响。4然而，临床医生的研究表明，此类干预措施可能不会被广泛使用。5，6缺乏关于这一主题的报道数据。因此，在这项以人群为基础的前列腺癌幸存者研究中，我们调查了支持性药物和干预措施的使用。方法前列腺癌治疗，您的经验)研究方法已在其他地方描述。7 Brieéy，6,559名前列腺癌幸存者(诊断于1995年1月1日至2010年3月31日期间确诊，2011年11月仍活着)，从爱尔兰共和国和北爱尔兰的基于人口的癌症登记中获得身份，被邀请完成一项邮寄调查。寻求有关治疗后任何时候经历过的后遗症(大小便失禁、阳萎、女性乳房发育、潮热、出汗、肠道问题、抑郁)的信息。每次检查后，男性都会被问到他们是否接受过任何缓解症状的药物或干预措施，如果是，他们接受了什么；常见干预的例子是-
Prostate cancer treatments are associated with various physical after-e ects, including urinary, sexual, and bowel symptoms.1 ese after-e ects can have an impact on survivors’ healthrelated quality of life (HRQoL).2 Pharmaceutical and surgical interventions are available to manage or ameliorate many of these after-e ects (eg, sildena
l citrate taken during and after radiotherapy improves sexual function),3 and their receipt has a positive impact on HRQoL.4 However, studies of clinicians suggest that such interventions may not be used widely.5,6 Patientreported data on this topic is lacking. erefore, we investigated the use of supportive medications and interventions in this population-based study of prostate cancer survivors. Methods e PiCTure (Prostate Cancer Treatment, Your Experience) study methods have been described elsewhere.7 Briey, 6,559 prostate cancer survivors 2-15 years after diagnosis (diagnosed during January 1, 1995-March 31, 2010, and alive in November 2011), identi
ed from population-based cancer registries in the Republic of Ireland and Northern Ireland, were invited to complete a postal survey. Information was sought on after-e ects (incontinence, impotence, gynaecomastia, hot ashes/sweats, bowel problems, depression) that had been experienced at any time after treatment. For each after-e ect, men were asked if they had received any medication or interventions to alleviate symptoms, and, if so, what they had received; examples of common interven-