Sensory Modulation Disorder Symptoms in Anorexia Nervosa and Bulimia Nervosa: A Pilot Study
Sensory Modulation Disorder Symptoms in Anorexia Nervosa and Bulimia Nervosa: A Pilot Study
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DOI：
10.1002/eat.22460
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发表时间：
2016-01-01
影响因子：
5.5
通讯作者：
Stein, Daniel
中科院分区：
文献类型：
--
作者：
Brand-Gothelf, Ayelet;Parush, Shula;Stein, Daniel
目的：神经性厌食症(AN)和神经性暴食症(BN)患者可能表现出调节感觉、生理和情感反应的能力降低。本研究的目的是评估AN和BN患者的感觉调节障碍(SMD)症状。方法：我们评估了女性青少年和青壮年住院的限制性神经性厌食症(AN-R；n=20)和BN(n=20)患者急性期的症状，并与27名女性对照。另一组20名AN-R住院患者在达到要求的体重后，在入院和出院时进行评估。受试者完成了评估进食障碍(ED)严重程度的标准化问卷和感觉反应性问卷(SRQ)。结果：与BN患者和对照组相比，An-R住院患者总体感觉过度反应以及味觉/味觉、前庭/动觉和躯体感觉/触觉SRQ的得分均高于BN患者。感觉过度反应的严重程度与ED相关的症状学在急性AN-R患者中被发现，在较小程度上，在体重恢复后。在体重恢复的An-R住院患者中，感觉过度反应的升高仍然存在。BN住院患者在SRQ的强度子量表上表现出更强的感觉反应不足，但在频率和组合SRQ维度上没有表现出更大的感觉反应不足。讨论：女性ANR住院患者在病情急性期和体重恢复后都表现出感觉过度反应，提示感觉过度反应可能代表了除营养不良影响之外与疾病本身有关的特征。BN患者的感觉反应不足的发现不太一致。(C)2015年威利期刊公司。
Objective: Individuals with anorexia nervosa (AN) and bulimia nervosa (BN) may exhibit reduced ability to modulate sensory, physiological, and affective responses. The aim of the present study is to assess sensory modulation disorder (SMD) symptoms in patients with AN and BN.Method: We assessed female adolescent and young adult inpatients with restrictive type anorexia nervosa (AN-R; n=20) and BN (n=20) evaluated in the acute stage of their illness, and 27 female controls. Another group of 20 inpatients with AN-R was assessed on admission and discharge, upon achieving their required weight. Participants completed standardized questionnaires assessing the severity of their eating disorder (ED) and the sensory responsiveness questionnaire (SRQ).Results: Inpatients with AN-R demonstrated elevated overall sensory over-responsiveness as well as elevated scores on the taste/gustatory, vestibular/kinesthetic and somatosensory/tactile SRQ modalities compared with patients with BN and controls. Significant correlations between the severity of sensory over-responsiveness and ED-related symptomatology were found in acutely-ill patients with AN-R and to a lesser extent, following weight restoration. Elevated sensory over-responsiveness was retained in weight-restored inpatients with AN-R. Inpatients with BN demonstrated greater sensory under-responsiveness in the intensity subscale of the SRQ, but not in the frequency and combined SRQ dimensions.Discussion: Female inpatients with ANR exhibited sensory over-responsiveness both in the acute stage of their illness and following weight restoration, suggesting that sensory over-responsiveness may represent a trait related to the illness itself above and beyond the influence of malnutrition. The finding for sensory under-responsiveness in BN is less consistent. (C) 2015 Wiley Periodicals, Inc.