Mouse color and wavelength-specific luminance contrast sensitivity are non-uniform across visual space
Mouse color and wavelength-specific luminance contrast sensitivity are non-uniform across visual space
复制标题
DOI：
10.7554/elife.31209
复制
发表时间：
2018-01-10
期刊：
影响因子：
7.7
通讯作者：
Reid, R. Clay
中科院分区：
文献类型：
--
作者：
Denman, Daniel J.;Luviano, Jennifer A.;Reid, R. Clay
哺乳动物的视觉行为以及这些行为背后的神经系统的反应是由亮度和颜色对比度驱动的。随着用于测量小鼠在视觉行为期间细胞类型特异性群体中的活性的工具不断改进，重要的是定义小鼠行为上可访问的亮度和颜色信息的程度。视锥视蛋白在小鼠视网膜中的非均匀分布可能使亮度和颜色敏感性两者复杂化;短（UV移位）和中间（蓝色/绿色）视锥视蛋白的相反梯度表明颜色辨别和波长特异性亮度对比敏感性可能随视网膜位置而不同。在这里，我们问如何以及小鼠可以区分颜色和波长特定的亮度变化在视觉空间。我们发现，小鼠能够区分颜色，并且能够在视锥视蛋白分布的视觉空间中更广泛地做到这一点。我们还发现了特定波长带的亮度灵敏度的差异。
Mammalian visual behaviors, as well as responses in the neural systems underlying these behaviors, are driven by luminance and color contrast. With constantly improving tools for measuring activity in cell-type-specific populations in the mouse during visual behavior, it is important to define the extent of luminance and color information that is behaviorally accessible to the mouse. A non-uniform distribution of cone opsins in the mouse retina potentially complicates both luminance and color sensitivity; opposing gradients of short (UV-shifted) and middle (blue/green) cone opsins suggest that color discrimination and wavelength-specific luminance contrast sensitivity may differ with retinotopic location. Here we ask how well mice can discriminate color and wavelength-specific luminance changes across visuotopic space. We found that mice were able to discriminate color and were able to do so more broadly across visuotopic space than expected from the cone-opsin distribution. We also found wavelength-band-specific differences in luminance sensitivity.