Noise in the nervous system.
Noise in the nervous system.
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DOI:
10.1038/nrn2258
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发表时间:
2008-04
影响因子:
34.7
通讯作者:
Wolpert, Daniel M.
中科院分区:
文献类型:
--
作者:
Faisal, A. Aldo;Selen, Luc P. J.;Wolpert, Daniel M.
Random disturbances of signals, termed ‘noise’, pose a fundamental problem for information processing and affect all aspects of nervous-system function. However, the nature, amount and impact of noise in the nervous system have only recently been addressed in a quantitative manner. Experimental and computational methods have shown that multiple noise sources contribute to cellular and behavioural trial-to-trial variability. We review the sources of noise in the nervous system, from the molecular to the behavioural level, and show how noise contributes to trial-to-trial variability. We highlight how noise affects neuronal networks and the principles the nervous system applies to counter detrimental effects of noise, and briefly discuss noise's potential benefits.
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