Decrease in prevalence of Buerger's disease in Japan.
Decrease in prevalence of Buerger's disease in Japan.
复制标题
日本布尔格氏病的患病率下降。
DOI：
10.1016/s0039-6060(98)70095-9
复制
发表时间：
1998
期刊：
影响因子：
3.8
通讯作者：
Yuji Nimura
中科院分区：
文献类型：
--
作者：
Masahiro Matsushita;N. Nishikimi;T. Sakurai;Yuji Nimura
背景Buerger病是一种外周动脉闭塞性疾病，在西方国家越来越少见，但在亚洲更常见。它是否是一种特定的疾病实体仍然存在争议。这项研究进行了调查的变化，在一个主要的机构在Japan.MethodsPatients与伯格病的患病率和特点收治名古屋大学医院1985年1月至1996年12月进行了回顾性研究。Buerger病入院诊断根据Shionoya的临床critics.ResultsA共105例Buerger病进行了评估，对126个入院; 58个是新的患者谁被接纳为初始治疗，和47例患者正在经历恶化的Buerger病，并有既往治疗史。1985年至1989年收治了46例新患者，但1990年至1996年仅收治了12例新患者（9 ± 3例/年vs 2 ± 2例/年，p = 0.0003）。在1985年至1989年期间，44例患者因疾病加重而入院，而在1990年至1996年期间仅发生24例此类入院（9 ± 3/年vs 3 ± 3/年，p = 0.0137）。在此期间，动脉粥样硬化性外周血管疾病的入院人数没有显著变化。在105例患者中，大多数（96%）为男性;疾病发作时的平均年龄为36 ± 8岁。入院时的主诉为坏疽/溃疡64%，静息痛13%，足跛行6%，小腿跛行6%，其他10%。结论在我们日本的机构，Buerger病的患病率似乎在下降。其临床特征没有改变。西方国家的流行率似乎也出现了类似的下降。（外科1998;124：498-502。）
BackgroundBuerger's disease is a peripheral arterial occlusive disease that is becoming rare in Western countries but is more common in Asia. Whether it is a specific disease entity remains controversial. This study was undertaken to investigate changes in the prevalence and characteristics of Buerger's disease at a major institution in Japan.MethodsPatients with Buerger's disease admitted to Nagoya University Hospital between January 1985 and December 1996 were studied retrospectively. Buerger's disease was diagnosed on admission according to Shionoya's clinical criteria.ResultsA total of 105 patients with Buerger's disease were evaluated on 126 admissions; 58 were new patients who were admitted for initial treatment, and 47 patients were experiencing a worsening of Buerger's disease and had a history of prior treatment. Forty-six new patients were admitted between 1985 and 1989, but only 12 new patients were admitted between 1990 and 1996 (9 ± 3/yr vs 2 ± 2/yr, p = 0.0003). Between 1985 and 1989, 44 patients were admitted because of disease exacerbation, whereas only 24 such admissions occurred between 1990 and 1996 (9 ± 3/yr vs 3 ± 3/yr, p = 0.0137). The number of admissions for atherosclerotic peripheral vascular disease did not change significantly in that period. Of the 105 patients, the majority (96%) were men; mean age at the time of disease onset was 36 ± 8 years. The chief complaint on admission was gangrene/ulcer in 64%, rest pain in 13%, foot claudication in 6%, calf claudication in 6%, and others in 10%.ConclusionsThe prevalence of Buerger's disease appears to be decreasing at our institution in Japan. Its clinical characteristics have not changed. A similar decrease in prevalence appears to have occurred in Western countries. (Surgery 1998;124:498-502.)