Adjuvant Chemotherapy in a Pregnant Woman With Endodermal Sinus Tumor of the Ovary
Adjuvant Chemotherapy in a Pregnant Woman With Endodermal Sinus Tumor of the Ovary
复制标题
卵巢内胚窦瘤孕妇的辅助化疗
DOI：
--
复制
发表时间：
2007
影响因子：
7.2
通讯作者：
Kazunori Ochiai
中科院分区：
文献类型：
--
作者：
M. Motegi;S. Takakura;Hirokuni Takano;Tadao Tanaka;Kazunori Ochiai
背景：妊娠期间使用化疗药物的情况很少见。我们描述一例妊娠合并恶性卵巢肿瘤的病例。病例：妊娠18周剖腹手术后，患者接受了三个疗程的顺铂、长春花碱和博莱霉素。妊娠 31 周时进行选择性剖腹产。产下一名正常婴儿，未观察到肿瘤复发的证据。产后第五个月发现肝脏转移。然而，经过三个疗程的顺铂、依托泊苷和博来霉素的治疗，该症状得到了成功治疗。初次治疗后 65 个月没有观察到复发的证据。结论：虽然无法根据单个病例评估化疗对胎儿的风险，但这一经验令人鼓舞。
BACKGROUND: The administration of chemotherapeutic drugs during pregnancy is rare. We describe a case of malignant ovarian tumor complicating pregnancy. CASE: After laparotomy at 18 weeks of gestation, the patient received three courses of cisplatin, vinblastine, and bleomycin. Elective cesarean delivery was performed at 31 weeks of gestation. A normal infant was delivered, and no evidence of tumor recurrence was observed. Metastasis to the liver was detected in the fifth month after delivery. However, this was treated successfully with three courses of cisplatin, etoposide, and bleomycin. There was no evidence of recurrence observed at 65 months after the initial treatment. CONCLUSION: Although the risk of chemotherapy to the fetus cannot be assessed based on a single case, this experience is encouraging.
DOI：
10.1097/01.ogx.0000083700.80693.da
发表时间：
2003-09
期刊：
The Journal of clinical investigation
影响因子：
--
作者：
S. Maynard;J. Min;J. Merchan;K. Lim;Jianyi Li;S. Mondal;T. Libermann;James P. Morgon;F. Sellke-F
通讯作者：
S. Maynard;J. Min;J. Merchan;K. Lim;Jianyi Li;S. Mondal;T. Libermann;James P. Morgon;F. Sellke-F
绝经前妇女的促性腺激素腺瘤分泌促卵泡激素并导致卵巢过度刺激。
DOI：
10.1210/jcem.80.2.7852525
发表时间：
1995
期刊：
The Journal of clinical endocrinology and metabolism.
影响因子：
--
作者：
Djerassi,A;Coutifaris,C;West,VA;Asa,SL;Kapoor,SC;Pavlou,SN;Snyder,PJ
通讯作者：
Snyder,PJ