Limited resources in a driven diffusion process.
Limited resources in a driven diffusion process.
复制标题
DOI：
10.1103/physrevlett.105.078102
复制
发表时间：
2010-08-13
影响因子：
8.6
通讯作者：
Thiel M
中科院分区：
文献类型：
--
作者：
Brackley CA;Romano MC;Grebogi C;Thiel M
在许多驱动扩散系统中，粒子的前进取决于周围环境中资源的可用性。在这类资源的供求平衡方面，我们面临着这样一种制度，即在有限的资源供应情况下，流量明显减少。在mRNA翻译的背景下，这代表了氨基酸-tRNA分子的有限可用性。在这种有限的资源制度中，还观察到氨基酸-tRNA的严重消耗。这些戏剧性的效果是至关重要的，我们的翻译的理解，也可能是重要的驱动扩散模型的许多其他应用。
The advance of particles in many driven diffusion systems depends on the availability of resources in the surrounding environment. In the balance between supply and demand of such resources we are confronted with a regime in which, under limited resource availability, the flow is markedly reduced. In the context of mRNA translation this represents the finite availability of amino acid-tRNA molecules. In this limited resources regime a severe depletion of amino acid-tRNAs is also observed. These dramatic effects are vital to our understanding of translation, and are likely to also be important for the many other applications of driven diffusion models.