Salivary immunoinflammatory proteins identify children with eosinophilic esophagitis.
Salivary immunoinflammatory proteins identify children with eosinophilic esophagitis.
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唾液免疫炎症蛋白可识别患有嗜酸性粒细胞性食管炎的儿童。
DOI：
10.1111/all.16040
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发表时间：
2024
期刊：
影响因子：
12.4
通讯作者：
Rajagopala,SeesandraV
中科院分区：
文献类型：
--
作者：
Hiremath,Girish;Wang,Yu;Correa,Hernan;Sheng,Quanhu;Rajagopala,SeesandraV
发表在《过敏》杂志上的一项研究表明，唾液免疫炎症蛋白可以作为一种侵入性较小的方法来识别患有嗜酸性粒细胞性食管炎 (EoE) 的儿童。目前，EoE 是通过侵入性手术来诊断的。该研究收集了 EoE 儿童和对照组儿童的唾液样本，并使用邻近延伸分析来分析蛋白质。研究结果表明，一组蛋白质可以准确地区分患有 EoE 的儿童和对照组，并区分 EoE 的不同亚型。这项研究表明唾液蛋白具有诊断潜力，可以作为 EoE 的非侵入性生物标志物，但需要进一步的研究来验证这些发现。[摘自文章]Allergy 的版权是 Wiley-Blackwell 的财产，未经版权所有者明确书面许可，不得将其内容复制或通过电子邮件发送到多个网站或发布到列表服务器。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。本摘要可能会被删节。不保证副本的准确性。用户应参阅该材料的原始发布版本以获取完整摘要。版权适用于所有摘要。
A study published in the journal Allergy suggests that salivary immunoinflammatory proteins could be used as a less invasive method for identifying children with eosinophilic esophagitis (EoE). Currently, EoE is diagnosed through invasive procedures. The study collected saliva samples from children with EoE and controls and used proximity extension analysis to analyze the proteins. The findings indicate that a panel of proteins could accurately distinguish children with EoE from controls and differentiate between different subtypes of EoE. This research suggests that salivary proteins have diagnostic potential and could serve as non-invasive biomarkers for EoE, but further research is needed to validate these findings.[Extracted from the article]Copyright of Allergy is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. Copyright applies to all Abstracts.
影响因子：
120.7
作者：
Muir, Amanda;Falk, Gary W.
通讯作者：
Falk, Gary W.