NEW CYTOPLASMIC GENETIC ELEMENT THAT CONTROLS 20S-RNA SYNTHESIS DURING SPORULATION IN YEAST
NEW CYTOPLASMIC GENETIC ELEMENT THAT CONTROLS 20S-RNA SYNTHESIS DURING SPORULATION IN YEAST
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DOI：
10.1128/jb.134.1.261-269.1978
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发表时间：
1978-01-01
影响因子：
3.2
通讯作者：
HABER, JE
中科院分区：
文献类型：
--
作者：
GARVIK, B;HABER, JE
在诱导酿酒酵母减数分裂和产孢的条件下，大多数菌株积累了20S RNA，占新合成RNA的15%。细胞积累这种新RNA物种的能力取决于细胞质遗传的显性遗传元件，但与先前鉴定的其他细胞质元件不同。合成20S RNA的能力不依赖于线粒体DNA。m DNA，翻译抑制因子。psi。这是一种携带URE3或双链杀伤RNA的遗传元素。所有检测到的20S-菌株都是非杀伤型菌株，尽管许多非杀伤型菌株是20S+。20S RNA的积累对孢子形成并不是必需的，即使它只由启动孢子形成的条件诱导。不能完成减数分裂的菌株在促进产孢的缺氮条件下仍能产生20S RNA。
Under conditions that induce meiosis and sporulation in Saccharomyces cerevisiae, most strains accumulate a 20S RNA, amounting to as much as 15% of the newly synthesized RNA. The ability of cells to accumulate this new RNA species depends on a dominant genetic element that is cytoplasmically inherited, but is distinct from the other cytoplasmic elements that were previously identified. The ability to synthesize 20S RNA does not depend on mitochondrial DNA, 2-.mu.m DNA, the translational suppressor .psi., the genetic element carrying URE3, or double-stranded killer RNA. All 20S- strains examined were also non-killers, although many non-killer strains were 20S+. Accumulation of 20S RNA is not essential for sporulation even though it is induced only by conditions that initiate sporulation. Strains that are unable to complete meiosis are still capable of producing 20S RNA when placed under the N starvation conditions that promote sporulation.