Apparent Diffusion Coefficient Reproducibility of the Pancreas Measured at Different MR Scanners Using Diffusion-Weighted Imaging

Apparent Diffusion Coefficient Reproducibility of the Pancreas Measured at Different MR Scanners Using Diffusion-Weighted Imaging
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DOI:
10.1002/jmri.24492
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发表时间:
2014-12-01
影响因子:
4.4
通讯作者:
Liu, Yuan
Liu, Yuan
中科院分区:
医学2区
文献类型:
--
作者:
Ye, Xiao-Hua;Gao, Jia-Yin;Liu, Yuan

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材料与方法24名健康志愿者分别在GE 1.5T、Siemens 1.5T和Philips 3.0T三台MR机上进行了连续三次弥散加权成像(DWI),并于12天后在同一台GE 1.5T上再次进行了DWI。测量胰腺的ADC值。采用配对t检验和Bland-Altman法对ADC值进行分析。(单位:10(-3)mm(2)/s),在GE 1.5T下测量(观察员1为2.24、2.01、1.88,观察员2为2.23、2.00、1.92)和Siemens 1.5T观察者1和观察者2分别为2.24、2.04、1.84和2.20、1.98、1.84,均显著高于Philips 3.0T(观察者1为2.06、1.80、1.56,观察者2为2.02、1.79、1.60)(P = 0.000-0.008)。GE 1.5T和Siemens 1.5T之间的ADC值无显著差异(P = 0.115-0.966),GE 1.5T成像会话1和2之间的ADC值无显著差异(P = 0.072-0.938)。一致性的平均差范围在GE 1.5T下,两台1.5T扫描仪之间的ADC值为-0.07-0.04 +/- 0.39-0.53,两台1.5T扫描仪之间的ADC值为-0.04-0.04 +/- 0.24-0.47。但是在具有相同场强的不同MR系统之间以及在相同MR系统处随时间显示出良好的再现性。J.磁共振Imaging 2014;40:1375-1381. (c)2013 Wiley Periodicals,Inc.
PurposeTo evaluate the reproducibility of the pancreatic apparent diffusion coefficient (ADC) measured at different MR scanners.Materials and MethodsTwenty-four healthy volunteers underwent three consecutive diffusion-weighted imaging (DWI) at a GE 1.5 Tesla (T), a Siemens 1.5T and a Philips 3.0T (session 1), and imaged again using the same protocol at the same GE 1.5T (session 2) 12 days later. The ADC values of pancreas were measured at all three MR scanners. Paired-sample t-test and the Bland-Altman method were used for ADC data analysis.ResultsThe individual mean ADC values of pancreatic head, body, and tail (in 10(-3)mm(2)/s) measured at GE 1.5T (2.24, 2.01, 1.88 for observer 1 and 2.23, 2.00, 1.92 for observer 2) and Siemens 1.5T (2.24, 2.04, 1.84 for observer 1 and 2.20, 1.98, 1.84 for observer 2) were significantly higher than those at Philips 3.0T (2.06, 1.80, 1.56 for observer 1 and 2.02, 1.79, 1.60 for observer 2) (P = 0.000-0.008). There was no significant difference of ADC values either between GE 1.5T and Siemens 1.5T (P = 0.115-0.966), or between imaging session 1 and 2 at GE 1.5T (P = 0.072-0.938). The range of mean difference limits of agreement (in 10(-3)mm(2)/s) was -0.07-0.04 +/- 0.39-0.53 between two 1.5T scanners, and -0.04-0.04 +/- 0.24-0.47 between two imaging sessions at GE 1.5T.ConclusionThe measured ADC values of pancreas are affected by the field strength of scanner, but show good reproducibility between different MR systems with same field strength and at the same MR system over time. J. Magn. Reson. Imaging 2014;40:1375-1381. (c) 2013 Wiley Periodicals, Inc.