Evaluation, diagnosis, and treatment of lead poisoning in a patient with occupational lead exposure: a case presentation.

Evaluation, diagnosis, and treatment of lead poisoning in a patient with occupational lead exposure: a case presentation.
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DOI:
10.1186/1745-6673-2-7
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发表时间:
2007-08-24
期刊:
Journal of occupational medicine and toxicology (London, England)
影响因子:
--
通讯作者:
Venkatesh, Thuppil
Venkatesh, Thuppil
中科院分区:
其他
文献类型:
--
作者:
Herman, D'souza Sunil;Geraldine, Menezes;Venkatesh, Thuppil

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在有毒重金属中,铅是世界上最严重的环境毒物之一。由于缺乏对铅的不良影响的认识,许多成年人和儿童在家中和工作场所接触铅会对健康造成危害,并造成经济损失。我们报告的情况下,22岁的男子在一个无组织的铅酸电池生产单位工作,抱怨全身疼痛,嗜睡,疲劳,肩关节疼痛,颤抖的手和手腕下降的历史较长。患者牙龈连接处有蓝线。中枢神经系统检查显示右腕及手指伸肌肌力为0级。反射:旋后肌-缺席,三头肌-弱和其他深腱反射-正常。入院期间进行的调查显示血红蛋白水平为8.3 g/dl,血铅水平为128.3 mug/dl。患者接受螯合治疗,同时进行积极的环境干预,并被建议不要返回相同的环境暴露情况。经过反复的螯合治疗,他已经显示出改善的迹象,目前正在随访。
Amongst toxic heavy metals, lead ranks as one of the most serious environmental poisons all over the world. Exposure to lead in the home and the workplace results in health hazards to many adults and children causing economic damage, which is due to the lack of awareness of the ill effects of lead. We report the case of a 22 year old man working in an unorganized lead acid battery manufacturing unit, complaining about a longer history of general body ache, lethargy, fatigue, shoulder joint pain, shaking of hands and wrist drop. Patient had blue line at gingivodental junction. Central nervous system (CNS) examination showed having grade 0 power of extensors of right wrist & fingers. Reflexes: Supinator- absent, Triceps- weak and other deep tendon reflexes- normal. Investigations carried out during the admission showed hemoglobin levels of 8.3 g/dl and blood lead level of 128.3 mug/dl. The patient was subjected to chelation therapy, which was accompanied by aggressive environmental intervention and was advised not to return to the same environmental exposure situation. After repeated course of chelation therapy he has shown the signs of improvement and is on follow up presently.