INCHING TOWARD REALITY - AN IMPROVED LIKELIHOOD MODEL OF SEQUENCE EVOLUTION
INCHING TOWARD REALITY - AN IMPROVED LIKELIHOOD MODEL OF SEQUENCE EVOLUTION
复制标题
DOI：
10.1007/bf00163848
复制
发表时间：
1992-01-01
影响因子：
3.9
通讯作者：
FELSENSTEIN, J
中科院分区：
文献类型：
--
作者：
THORNE, JL;KISHINO, H;FELSENSTEIN, J
我们之前的进化模型被概括为允许近似处理多碱基插入和缺失以及取代率的区域异质性。 开发了包含这些概括的参数估计和对齐程序。 模拟用于评估参数估计过程的准确性，并包括推断对齐的示例。
Our previous evolutionary model is generalized to permit approximate treatment of multiple-base insertions and deletions as well as regional heterogeneity of substitution rates. Parameter estimation and alignment procedures that incorporate these generalizations are developed. Simulations are used to assess the accuracy of the parameter estimation procedure and an example of an inferred alignment is included.