Stem cell niches: famished Paneth cells, gluttonous stem cells.

Stem cell niches: famished Paneth cells, gluttonous stem cells.
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干细胞生态位:饥饿的潘氏细胞、贪食干细胞。

DOI:
10.1016/j.cub.2012.06.017
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发表时间:
2012
期刊:
Current biology : CB
影响因子:
--
通讯作者:
Shivdasani,RameshA
Shivdasani,RameshA
中科院分区:
--
文献类型:
--
作者:
Kim,Tae-Hee;Shivdasani,RameshA

文献摘要

相似文献

成体组织干细胞适应环境变化。一项针对小鼠肠道的新研究表明,热量限制会导致潘氏细胞抑制 mTORC1 信号传导;这反过来又刺激邻近干细胞的增殖。
Adult tissue stem cells adjust to environmental changes. A new study in the mouse intestine reveals that caloric restriction causes Paneth cells to repress mTORC1 signaling; this in turn stimulates proliferation of neighboring stem cells.