Soft tissue elastometer
Soft tissue elastometer
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DOI：
10.1016/j.medengphy.2007.02.007
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发表时间：
2008-03-01
影响因子：
2.2
通讯作者：
Sarvazyan, A.
中科院分区：
文献类型：
--
作者：
Egorov, V.;Tsyuryupa, S.;Sarvazyan, A.
我们开发了一种名为“组织弹性计”（TE）的设备，用于评估软组织的杨氏模量。将软组织样本压缩在电子天平的载物板和具有小圆形尖端的线性致动压头之间。该设备的硬件设计，使得半无限介质的变形模型是适用于计算的杨氏模量的试样从他们收集的力-位移数据。在固化的有机硅混合物的长条上进行力-伸长率测量，以在10-400 kPa的杨氏模量范围内产生TE的校准的组织模拟测试样品。当使用TE进行测试时，硅胶样品的杨氏模量显示出在其校准值的1-10%范围内的准确度。还对切除的组织样品（新鲜商店购买的家禽乳房;牛肝、肾、后腿;猪）进行了测试，并证明弹性测量的重复性在8- 14%的范围内。结果表明，TE可以有效地用于实验室和临床环境中，以评估组织的弹性模量。(c)2007年妇女平等问题国际研究所。由爱思唯尔有限公司出版。保留所有权利。
We have developed a device entitled the 'Tissue Elastometer' (TE) for evaluating the Young's modulus of soft tissues. Soft tissue specimens are compressed between the object plate of an electronic balance and a linearly actuated indenter with a small rounded tip. The hardware of the device was designed such that a deformation model for semi-infinite media is applicable for calculating the Young's modulus of test specimens from their collected force-displacement data. Force-elongation measurements were performed on long strips of cured silicone mixtures to produce calibrated, tissue-mimicking test samples for the TE in a Young's modulus range of 10-400 kPa. When tested with the TE, the Young's moduli of the silicone samples demonstrated accuracy to within 1-10% of their calibrated values. Testing on excised tissue samples (fresh store-bought poultry breast; bovine liver, kidneys, hind shanks; porcine)was also performed, and a repeatability of elasticity measurements was demonstrated in the range of 8-14%. Results indicate that the TE can be effectively used in laboratory and clinical environments to evaluate the elasticity modulus of tissues. (c) 2007 IPEM. Published by Elsevier Ltd. All rights reserved.