Respiratory effects are associated with the number of ultrafine particles

Respiratory effects are associated with the number of ultrafine particles
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DOI:
10.1164/ajrccm.155.4.9105082
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发表时间:
1997-04-01
影响因子:
24.7
通讯作者:
Heyder, J
Heyder, J
中科院分区:
医学1区
文献类型:
--
作者:
Peters, A;Wichmann, HE;Heyder, J

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在德国东部的埃尔富特研究了细颗粒和超细颗粒物与呼吸系统健康的关系。27名不吸烟的哮喘患者每天记录他们的呼气峰流速(PEF)和呼吸系统症状。1991-1992年冬季,用气溶胶谱仪测定了大气颗粒物的粒径分布,粒径范围在0.01 ~ 2.5 μ m之间,绝大多数(73%)为超细颗粒(直径小于0.1 μ m),而苔藓:质量(82%)的可归因于尺寸范围为0.1至0.5 μ m的tee颗粒。由于这两个部分没有相似的时间过程(相关系数r = 0.51),因此可以比较它们的健康影响。这两个部分都与PEF降低以及白天咳嗽和不适感增加相关。超细颗粒物数量的5 d均值对健康的影响大于细颗粒物质量的5 d均值,而且超细颗粒物数量对PEF的影响大于小于10 μ m的颗粒物(PM(10))。因此,本研究表明,环境颗粒物的粒径分布有助于阐明环境气溶胶的健康影响的属性。
The association between fine and ultrafine particles and respiratory health was studied in adults with a history of asthma in Erfurt Eastern Germany, Twenty-seven nonsmoking asthmatics recorded their peak expiratory flow (PEF) and respiratory symptoms daily. The size distribution of ambient particles in the range of 0.01 to 2.5 mu m was determined with an aerosol spectrometer during the winter season 1991-1992, Most of the particles (73%) were in the ultrafine fraction (smaller than 0.1 mu m in diameter), whereas moss: of the mass (82%) was attributable tee particles in the size range of 0.1 to 0.5 mu m. Because these two fractions did not have similar time courses (correlation coefficient r = 0.51), a comparison of their health effects was possible, Both fractions were associated with a decrease of PEF and an increase in cough and feeling ill during the day. Health effects of the 5-d mean of the number of ultrafine particles were larger than those of the mass of the fine particles, In addition, the effects of the number of the ultrafine particles on PEF were stronger than those of particulate matter smaller than 10 mu m (PM(10)). Therefore, the present study suggests that the size distribution of ambient particles helps to elucidate the properties of ambient aerosols responsible for health effects.