Transformation of a Primitive Myxoid Mesenchymal Tumor of Infancy to an Undifferentiated Sarcoma: A First Reported Case
Transformation of a Primitive Myxoid Mesenchymal Tumor of Infancy to an Undifferentiated Sarcoma: A First Reported Case
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DOI：
10.1097/mph.0000000000000107
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发表时间：
2015-03-01
影响因子：
1.2
通讯作者：
Bouron-Dal Soglio, Dorothee
中科院分区：
文献类型：
--
作者：
Guilbert, Marie-Christine;Rougemont, Anne-Laure;Bouron-Dal Soglio, Dorothee
一个8个月大的女孩接受手术切除宫颈肿块，组织学诊断为婴儿期原始黏液样间质肿瘤（PMMTI）。在最初的手术干预后5年多，肿瘤局部复发，并有许多远处转移。该肿瘤的组织学形态符合未分化高级别肉瘤的诊断。PMMTI是一种最近被发现的婴儿期低分化的纤维母细胞软组织肿瘤，至少具有边缘性生物学行为，特点是局部复发和转移的可能性。我们在此报告第一例PMMTI转化为未分化的高级别肉瘤。
An 8-month-old girl underwent surgical resection of a cervical mass with histologic diagnosis of a primitive myxoid mesenchymal tumor of infancy (PMMTI). More than 5 years after the initial surgical intervention, the tumor recurred locally, with numerous distant metastases. The histologic morphology of this tumor was compatible with a diagnosis of an undifferentiated high-grade sarcoma. PMMTI is a recently described poorly differentiated fibroblastic soft-tissue tumor of infancy, of at least borderline biological behavior, characterized by local recurrence and a potential to metastasize. We present here the first case of a transformation of a PMMTI into an undifferentiated high-grade sarcoma.