Iron Deficiency in the Absence of Anemia Impairs the Perception of Health-Related Quality of Life of Patients with Inflammatory Bowel Disease
Iron Deficiency in the Absence of Anemia Impairs the Perception of Health-Related Quality of Life of Patients with Inflammatory Bowel Disease
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DOI：
10.1097/mib.0000000000000768
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发表时间：
2016-06-01
影响因子：
4.9
通讯作者：
Borruel, Natalia
中科院分区：
文献类型：
--
作者：
Herrera-deGuise, Claudia;Casellas, Francesc;Borruel, Natalia
背景：贫血是炎症性肠病（IBD）的常见并发症，并导致健康相关生活质量（HRQOL）恶化。缺铁（ID）是一种普遍的潜在因素，存在于高达90%的患者中。在没有贫血的情况下，目前尚不清楚ID在多大程度上影响IBD患者的HRQOL。我们的目的是确定是否ID没有贫血的负面影响正常的感知HRQOL IBD患者在remission.Methods：我们进行了一项前瞻性，横断面研究IBD患者在缓解无贫血。采集血液样本以确定铁状态，患者完成炎症性肠道疾病问卷-36。根据血清铁蛋白确定ID
Background:Anemia is a common complication of inflammatory bowel disease (IBD) and contributes to the deterioration of health-related quality of life (HRQOL). Iron deficiency (ID) is a prevalent underlying factor, present in up to 90% of patients. In the absence of anemia, it is unclear as to what extent ID can affect HRQOL in patients with IBD. Our aim was to determine whether ID without anemia negatively affects normal perception of HRQOL in patients with IBD in remission.Methods:We conducted a prospective, cross-sectional study in patients with IBD in remission without anemia. Blood samples were obtained to determine iron status, and patients completed the Inflammatory Bowel Disease Questionnaire-36. ID was defined on serum ferritin