A Comparison of Psychosocial and Cognitive Functioning Between Depressed and Non-Depressed Patients with Cannabis Dependence

A Comparison of Psychosocial and Cognitive Functioning Between Depressed and Non-Depressed Patients with Cannabis Dependence
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DOI:
10.1080/10550887.2010.489444
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发表时间:
2010-01-01
影响因子:
2.3
通讯作者:
Levin, Frances R.
Levin, Frances R.
中科院分区:
医学4区
文献类型:
--
作者:
Secora, Alex M.;Eddie, David;Levin, Frances R.

文献摘要

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大麻使用和抑郁症被认为会损害认知能力和心理社会功能。这两种疾病同时发生可能会加剧这些诊断的负面影响。在这项研究中,作者使用加州计算机化评估包作为认知性能指标,成瘾严重程度指数作为心理社会功能指标,比较大麻依赖者和抑郁或不抑郁的个体(N = 108:54只大麻依赖者,54只大麻依赖者和抑郁或心境恶劣)。正如所预测的那样,患有抑郁症的大麻依赖者比单独依赖大麻的人表现出更多的心理障碍。然而,与作者的假设相反,大麻依赖伴发抑郁症的个体在某些加州计算机评估包模块中显示出的认知障碍比单独依赖大麻的个体少。根据作者的结果,他们得出结论,大麻依赖和抑郁症的叠加效应可能仅限于心理社会领域,可能不会扩展到认知功能。
Cannabis use and depressive disorders are thought to impair cognitive performance and psychosocial functioning. Both disorders co-occurring may compound the negative effects of these diagnoses. In this study, the authors used the California Computerized Assessment Package as the cognitive performance measure and the Addiction Severity Index as the psychosocial functioning measure to compare individuals who were cannabis dependent and either depressed or not depressed (N= 108: 54 cannabis dependent only, 54 cannabis dependent and depressed or dysthymic). As predicted, cannabis dependent individuals with comorbid depression showed more psychosocial impairment than individuals with cannabis dependence alone. However, contrary to the authors' hypothesis, individuals who were cannabis dependent with comorbid depression showed less cognitive impairment in some California Computerized Assessment Package modules than individuals with cannabis dependence alone. Based on the authors' results, they concluded that the additive effects of cannabis dependency and depression may only be limited to psychosocial domains and may not extend to cognitive functioning.