Lessons from sudden coronary death - A comprehensive morphological classification scheme for atherosclerotic lesions

Lessons from sudden coronary death - A comprehensive morphological classification scheme for atherosclerotic lesions
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DOI:
10.1161/01.atv.20.5.1262
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发表时间:
2000-05-01
影响因子:
8.7
通讯作者:
Schwartz, SM
Schwartz, SM
中科院分区:
医学1区
文献类型:
--
作者:
Virmani, R;Kolodgie, FD;Schwartz, SM

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这篇综述将重新考虑当前的范式,以理解动脉粥样硬化病变进展的关键和最后步骤。该方案主要是戴维斯及其同事对尸检组织的观察的结果,1,2断言动脉粥样硬化性冠状动脉疾病的死亡原因是晚期动脉粥样硬化病变破裂。虽然这种假设可能部分正确,但最近的尸检研究表明它是不完整的。
This review will reconsider the current paradigm for understanding the critical, final steps in the progression of atherosclerotic lesions. That scheme, largely an outgrowth of observations of autopsy tissues by Davies and colleagues, 1, 2 asserts that the cause of death in atherosclerotic coronary artery disease is rupture of an advanced atherosclerotic lesion. Although this assumption may be partially true, recent autopsy studies suggest that it is incomplete.