A Modified Symblepharon Ring for Sutureless Amniotic Membrane Patch to Treat Acute Ocular Surface Burns
A Modified Symblepharon Ring for Sutureless Amniotic Membrane Patch to Treat Acute Ocular Surface Burns
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DOI：
10.1097/bcr.0b013e318239f9b9
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发表时间：
2012-03-01
影响因子：
1.4
通讯作者：
Wang, Zhichong
中科院分区：
文献类型：
--
作者：
Liang, Xuanwei;Liu, Zhiping;Wang, Zhichong
本研究的目的是评价一种使用改良的眼球粘连环将羊膜(AM)贴片固定在眼表治疗急性眼烧伤的无缝合技术。急性眼烧伤患者75例，共75只眼，均为III~VI级。他们被随机分为两组。39只眼接受改良的粘连眼环的无缝线AM补片，另外36只眼接受常规缝合的AM补片作为对照。记录上皮化时间、上皮化率、角膜新生血管和并发症。未缝合组手术时间和上皮关闭时间均明显短于缝合组(P<；0.01)。未缝合组再上皮化率高于缝合组(P<；0.05)。未缝合组血管形成率和睑粘连发生率低于缝合组(P<；0.05)。结膜囊收缩在未缝合组中仅见于V、VI级者，且晚于缝合组(P<；0.05)。该方法操作简单、创伤小、创伤小，与对照组相比效果更好。(J Burn Care Res 2012；33：e32-e38)
The objective of this study is to evaluate a sutureless technique by using a modified symblepharon ring to fix an amniotic membrane (AM) patch on the ocular surface to treat acute ocular burns. Seventy-five patients with acute ocular burns of total 75 eyes graded III to VI were enrolled in this study. They were randomly divided into two groups. Thirty-nine eyes received the sutureless AM patch with a modified symblepharon ring, and the other 36 eyes underwent the conventional sutured AM patch as control. The time and the rate of epithelialization, corneal neovascularization, and complications were recorded. Both the operation time and the time to epithelial closure in the sutureless group were much shorter than that in the suture group (P < .01). The rate of reepithelialization in the sutureless group was higher than in the suture group (P < .05). The rate of the vascularization and symblepharon were lower in the sutureless group than in the suture group (P < .05). The conjunctival sac contraction occurred only in the eyes with grade V and VI in the sutureless group and was later than in the suture group (P < .05). This modified method is simple, minimally invasive, free from trauma, and more effective compared with controls. (J Burn Care Res 2012;33:e32-e38)