Evaluation of Senegal's prevention of mother to child transmission of HIV (PMTCT) program data for HIV surveillance.
Evaluation of Senegal's prevention of mother to child transmission of HIV (PMTCT) program data for HIV surveillance.
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DOI：
10.1186/s12879-018-3504-z
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发表时间：
2018-11-20
影响因子：
3.7
通讯作者：
Mboup S
中科院分区：
文献类型：
--
作者：
Diouf O;Gueye-Gaye A;Sarr M;Mbengue AS;Murrill CS;Dee J;Diaw PO;Ngom-Faye NF;Diallo PAN;Suarez C;Gueye M;Mboup A;Toure-Kane C;Mboup S
随着预防母婴传播（PMTCT）服务在塞内加尔的扩大，人们越来越有兴趣使用PMTCT项目数据来代替进行基于非关联匿名检测（UAT）的ANC哨点监测。因此，2011-2012年进行了一次评估，以确定在过渡到使用预防母婴传播规划数据进行监测时需要解决的差距。我们进行了分析，以评估艾滋病毒流行率以及哨点监测和预防母婴传播艾滋病毒检测结果之间的一致性。此外，在哨点监测期间（2011年12月至2012年3月）和之前3个月，对预防母婴传播项目登记和数据进行了数据质量评估。最后，我们还评估了选择偏差，即产前诊所登记的所有妇女的艾滋病毒感染率与接受预防母婴传播艾滋病毒检测的妇女的艾滋病毒感染率之间的百分比差异。使用常规PMTCT HIV检测数据的中位站点HIV患病率为1.1% (IQR: 1.0)，而使用UAT HIV哨点监测数据的中位站点患病率为1.0% （IQR: 1.6）。与哨点监测相比，PMTCT艾滋病毒检测结果的阳性一致性（PPA）为85.1% (95% CI 77.2-90.7%)，阴性一致性百分比（PNA）为99.9% （95% CI 99.8-99.9%）。根据UAT，总体艾滋病毒流行率与接受预防母婴传播艾滋病毒检测的妇女和拒绝接受艾滋病毒检测的妇女相同，百分比偏差为0.00%。对于预防母婴传播的几个关键变量，包括“提供艾滋病毒检测”（85.2%）、“接受艾滋病毒检测”（78.0%）或“完成艾滋病毒检测”（58.8%），具有完整有效数据的登记记录所占比例低于世卫组织90%的基准。PPA为85.1，低于世卫组织96.6%的基准，而许多关键的预防母婴传播变量的综合数据效度和完整性率低于世卫组织90%的基准。这些结果表明，塞内加尔将需要加强现场艾滋病毒检测的质量，改进项目数据收集做法，为将预防母婴传播数据用于监测目的做准备。
With the expansion of Prevention of Mother to Child Transmission (PMTCT) services in Senegal, there is growing interest in using PMTCT program data in lieu of conducting unlinked anonymous testing (UAT)-based ANC Sentinel Surveillance. For this reason, an evaluation was conducted in 2011–2012 to identify the gaps that need to be addressed while transitioning to using PMTCT program data for surveillance. We conducted analyses to assess HIV prevalence rates and agreements between Sentinel Surveillance and PMTCT HIV test results. Also, a data quality assessment of the PMTCT program registers and data was conducted during the Sentinel Surveillance period (December 2011 to March 2012) and 3 months prior. Finally, we also assessed selection bias, which was the percentage difference from the HIV prevalence among all women enrolled in the antenatal clinic and the HIV prevalence among women who accepted PMTCT HIV testing. The median site HIV prevalence using routine PMTCT HIV testing data was 1.1% (IQR: 1.0) while the median site prevalence from the UAT HIV Sentinel Surveillance data was at 1.0% (IQR: 1.6). The Positive per cent agreement (PPA) of the PMTCT HIV test results compared to those of the Sentinel Surveillance was 85.1% (95% CI 77.2–90.7%), and the percent-negative agreement (PNA) was 99.9% (95% CI 99.8–99.9%). The overall HIV prevalence according to UAT was the same as that found for women accepting a PMTCT HIV test and those who refused, with percent bias at 0.00%. For several key PMTCT variables, including “HIV test offered” (85.2%), “HIV test acceptance” (78.0%), or “HIV test done” (58.8%), the proportion of records in registers with combined complete and valid data was below the WHO benchmark of 90%. The PPA of 85.1 was below the WHO benchmarks of 96.6%, while the combined data validity and completeness rates was below the WHO benchmark of 90% for many key PMTCT variables. These results suggested that Senegal will need to reinforce the quality of onsite HIV testing and improve program data collection practices in preparation for using PMTCT data for surveillance purposes.
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DOI：
10.1097/qai.0b013e31815724e7
发表时间：
2007-11-01
影响因子：
3.6
作者：
Fabiani, Massimo;Yoti, Zabulon;Declich, Silvia
通讯作者：
Declich, Silvia
影响因子：
8.5
作者：
Dee, Jacob;Garcia Calleja, Jesus M;Swaminathan, Mahesh
通讯作者：
Swaminathan, Mahesh
影响因子：
3.8
作者：
Hladik, W;Masupu, K;Marum, LH
通讯作者：
Marum, LH
影响因子：
3.3
作者：
Seguy, Nicole;Hladik, Wolfgang;Diaz, Theresa
通讯作者：
Diaz, Theresa
影响因子：
3.5
作者：
Parekh, Bharat S.;Kalou, Mireille B.;Nkengasong, John N.
通讯作者：
Nkengasong, John N.