Impact of Weekend Admissions on Quality of Care and Outcomes in Patients With Acute Myeloid Leukemia
Impact of Weekend Admissions on Quality of Care and Outcomes in Patients With Acute Myeloid Leukemia
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DOI：
10.1002/cncr.25086
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发表时间：
2010-08-01
期刊：
影响因子：
6.2
通讯作者：
Sekeres, Mikkael A.
中科院分区：
文献类型：
--
作者：
Bejanyan, Nelli;Fu, Alex Z.;Sekeres, Mikkael A.
背景：周末期间医院服务预计会减少，这可能导致治疗或获得医疗程序的延误。作者调查了新诊断的急性髓性白血病（AML）患者在周末和工作日住院并接受诱导化疗的护理质量和临床结果。方法：这项回顾性随访研究纳入了1994-2008年在克利夫兰诊所接受阿糖胞苷诱导化疗的422例AML患者。质量指标包括三腔导管（TLC）放置时间、诱导化疗时间、住院时间（LOS）、早期死亡（化疗15天内）和30天死亡率。通过线性、分类和生存分析的方法，测试这些与AML生存和病因的已知预测因子的关联。结果：23%的入院患者（n = 422）发生在周末（n = 103）。与年轻的（年老的）相比
BACKGROUND: Hospital services are expectantly reduced over the weekend, which may result in a delay in treatment or in obtainment of medical procedures. The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekdays and treated with induction chemotherapy. METHODS: This retrospective follow-up study involved 422 AML patients treated with cytarabine-based induction chemotherapy at Cleveland Clinic from 1994-2008. Quality outcome measures included time to triple-lumen catheter (TLC) placement, time to induction chemotherapy, length of stay (LOS), early death (within 15 days of chemotherapy), and 30-day mortality. These were tested for the association with known predictors of AML survival and etiology by the methods of linear, categorical, and survival analyses. RESULTS: Twenty-three percent of all admissions (n = 422) occurred over the weekend (n = 103). Compared with younger (aged