Influence of medical conditions on executive and memory functions in low socioeconomic status African Americans
Influence of medical conditions on executive and memory functions in low socioeconomic status African Americans
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DOI：
10.1016/j.acn.2007.05.003
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发表时间：
2007-08-01
影响因子：
2.6
通讯作者：
Zonderman, Alan B.
中科院分区：
文献类型：
--
作者：
Nguyen, Ha T.;Evans, Michele K.;Zonderman, Alan B.
我们检查了总共病评分和特定慢性病（包括心血管疾病、肌肉骨骼疾病、糖尿病、中风、高血压和癌症）与四个不同年龄组的几个认知领域的关联：年轻人（18-34岁）、年轻中年人（35-50岁）、中年人（51-64岁）和老年人（51-64岁） >64）。对 384 名非裔美国人进行了认知测试，测量整体能力、执行功能、记忆功能和感知速度能力。通过总结慢性病的数量来计算总合并症评分。结果显示，总合并症评分与总样本中的执行和记忆功能呈负相关。除最年轻的群体外，中风是所有年龄组表现不佳的唯一显着预测因素，但与老年人相比，较年轻的年龄组的影响更大。这些结果表明，医疗状况对特定领域任务的影响可能会因年龄而改变。 (C) 2007 年国家神经心理学研究院。由爱思唯尔有限公司出版。保留所有权利。
We examined the association of total comorbid score and specific chronic conditions including cardiovascular diseases, musculoskeletal conditions, diabetes mellitus, stroke, hypertension, and cancer with several cognitive domains across four different age groups: young adults (ages 18-34), young middle-aged adults (ages 35-50), middle-aged adults (ages 51-64), and older adults (ages >64). Cognitive tests measuring global ability, executive function, memory function, and perceptual speed ability were administered to 384 African Americans. Total comorbid score was computed by summing up the number of chronic conditions. Results showed an inverse association between total comorbid scores and executive and memory functions in the total sample. With the exception of the youngest group, stroke was the only prominent predictor of poor performance for all age groups, but the impact was greater in the younger age groups compared with older adults. These results suggest that the impact of medical conditions on domain specific tasks may be modified by age. (C) 2007 National Academy of Neuropsychology. Published by Elsevier Ltd. All rights reserved.