Depression history as a moderator of relations between cortisol and shame responses to social-evaluative threat in young adults.
Depression history as a moderator of relations between cortisol and shame responses to social-evaluative threat in young adults.
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DOI：
10.1016/j.biopsycho.2015.05.007
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发表时间：
2015-07
影响因子：
2.6
通讯作者：
Garber J
中科院分区：
文献类型：
--
作者：
Hellman N;Morris MC;Rao U;Garber J
皮质醇和羞耻感的变化通常是由涉及社会评价威胁的社会心理压力引起的。根据社会自我保护理论，这种协调的心理生物学反应是适应性的。然而，有抑郁史的人可能会表现出对急性应激源的皮质醇反应减弱，这可能会干扰协调的皮质醇和羞耻反应。本研究探讨了皮质醇和羞耻反应的心理社会压力任务的年轻人谁在他们的抑郁症的历史不同（56缓解抑郁症，46从来没有抑郁症）之间的时间关系。滞后效应多层次模型显示，抑郁史调节皮质醇水平和羞耻等级之间的关系25至55分钟后。这些相互作用的模式是相似的：而较高的皮质醇水平预测增加的羞耻在从不抑郁的个人，皮质醇水平无关的羞耻反应缓解抑郁的个人。研究结果表明，在有抑郁症史的个体中，皮质醇和羞耻感对压力的反应之间存在分离。
Changes in cortisol and shame are commonly elicited by psychosocial stressors involving social-evaluative threat. According to social self preservation theory, this coordinated psychobiological response is adaptive. Individuals with a history of depression, however, may exhibit diminished cortisol reactivity to acute stressors, which could interfere with coordinated cortisol and shame responses. The present study examined temporal relations between cortisol and shame responses to a psychosocial stress task in young adults who varied in their history of depression (56 remitted-depressed, 46 never-depressed). Lagged effects multilevel models revealed that depression history moderated relations between cortisol levels and shame ratings 25 to 55 minutes later. The pattern of these interactions was similar: whereas higher cortisol levels predicted increases in shame in never-depressed individuals, cortisol levels were unrelated to shame responses in remitted-depressed individuals. Findings suggest a dissociation between cortisol and shame responses to stress in individuals with a history of depression.