Acute respiratory distress syndrome: CT abnormalities at long-term follow-up

Acute respiratory distress syndrome: CT abnormalities at long-term follow-up
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DOI:
10.1148/radiology.210.1.r99ja2629
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发表时间:
1999-01-01
期刊:
影响因子:
19.7
通讯作者:
Hansell, DM
Hansell, DM
中科院分区:
医学1区
文献类型:
--
作者:
Desai, SR;Wells, AU;Hansell, DM

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目得:记录异常的计算机断层扫描(CT)在成人幸存者的急性呼吸窘迫综合征(ARDS),以确定在急性期和随访期间的CT模式之间的关系,并评估机械通气对CT abnormals.MATERIALS的发展的影响和方法:薄切片CT扫描获得在急性疾病和随访27例ARDS患者。结果:在随访CT中,网状模式是最常见的(23例患者[85%])和广泛的CT异常,具有显著的前部分布(前部分布多于后部分布,P <0.001)。随访时的网状结构与急性期脑实质严重浑浊程度呈负相关(斯皮尔曼r = -0.26,P <0.001)。随访CT时网状结构的范围与机械通气的总持续时间独立相关(P = .02),但与压力控制反比例通气的持续时间密切相关(P < .001)。呈网状,前部分布明显,是ARDS幸存者随访CT的常见结果,与压力控制反比例通气的持续时间密切相关。
PURPOSE: To document abnormalities at computed tomography (CT) in adult survivors of acute respiratory distress syndrome (ARDS), to determine the relationships between CT patterns during the acute phase and at follow-up, and to assess the effects of mechanical ventilation on the development of CT abnormalities.MATERIALS AND METHODS: Thin-section CT scans were obtained during the acute illness and at follow-up in 27 patients with ARDS. The extent and distribution of individual CT patterns were independently analyzed.RESULTS: At follow-up CT, a reticular pattern was the most prevalent (23 patients [85%]) and extensive CT abnormality, with a striking anterior distribution (more anterior distribution than posterior distribution, P < .001). A reticular pattern at follow-up was inversely correlated with the extent of intense parenchymal opacification on scans obtained during the acute illness (Spearman r = -0.26; P < .001). The extent of a reticular pattern at follow-up CT was independently related to the total duration of mechanical ventilation (P = .02) but was most strongly related to the duration of pressure-controlled inverse-ratio ventilation (P < .001).CONCLUSION: A reticular pattern, with a striking anterior distribution, is a frequent finding of follow-up CT in ARDS survivors and is most strongly related to the duration of pressure-controlled inverse-ratio ventilation.