LOW-STAGE CLEAR-CELL CARCINOMA OF THE ENDOMETRIUM
LOW-STAGE CLEAR-CELL CARCINOMA OF THE ENDOMETRIUM
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DOI：
10.1097/00000478-199507000-00004
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发表时间：
1995-07-01
影响因子：
5.6
通讯作者：
SILVA, EG
中科院分区：
文献类型：
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作者：
MALPICA, A;TORNOS, C;SILVA, EG
子宫内膜透明细胞癌是一种相对罕见的恶性肿瘤，被认为是最具侵袭性的子宫内膜癌类型之一。为了评估低期(I期和II期)子宫内膜CCC的行为，我们回顾了从1963年到1990年在德克萨斯大学安德森癌症中心看到的17例这样的病例。患者年龄52~81岁。15例为单纯CCC，2例以CCC为主，病灶为子宫内膜样腺癌，FIGO分级为I级。在研究进行时，6名患者活着，没有患病，1名患者患有疾病，5名患者死于其他原因，5名患者死于疾病。估计存活率为71%。子宫内膜样腺癌FIGO III级和子宫乳头状浆液性癌的5年生存率估计分别为73%和39%。我们的结论是，低期子宫内膜癌患者的生存率与子宫内膜样腺癌FIGO III级患者相似，而优于类似分期的子宫乳头状浆液性癌患者。
Clear-cell carcinoma (CCC) of the endometrium is a relatively rare malignancy that is considered to be one of the most aggressive types of endometrial carcinoma. To evaluate the behavior of low-stage (stages I and II) CCC of the endometrium, we retrospectively reviewed 17 such cases seen at The University of Texas M.D. Anderson Cancer Center from 1963 to 1990. Patients' ages ranged from 52 to 81 years. Fifteen cases were pure CCC, and two cases were predominantly CCC with a focus of endometrioid adenocarcinoma FIGO grade I. All patients have been followed-up for at least 3 years. At the time of the study, six patients were alive without disease, one patient was alive with disease, five had died of other causes, and five had died of disease. The estimated survival rate was 71%. Estimated 5-year survival rates for endometrioid adenocarcinoma FIGO grade III and uterine papillary serous carcinoma are 73 and 39%, respectively. We conclude that patients with low-stage CCC of the endometrium have a survival rate similar to that of patients with endometrioid adenocarcinoma FIGO grade III and better than that of patients with uterine papillary serous carcinoma of similar stages.