A new diterpenoid alkaloid isolated from Delphinium caeruleum
A new diterpenoid alkaloid isolated from Delphinium caeruleum
复制标题
从翠雀花中分离出一种新的二萜生物碱
DOI：
10.1016/s1875-5364(17)30007-9
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发表时间：
2017-01-01
影响因子：
4.6
通讯作者：
Zhu Chen-Chen
中科院分区：
文献类型：
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作者：
Lin Chao-Zhan;Liu Zhu-Jie;Zhu Chen-Chen
本研究旨在测定飞燕草（Delphinium caeruleum Jacq）化学成分。前综眼. .采用硅胶、ODS和Sephadex LH-20柱层析对其化学成分进行分离纯化。通过红外光谱、质谱和核磁共振对其结构进行了表征。得到10个化合物，分别鉴定为：茶树碱A(1)、lycoctonine(2)、塔里碱B(3)、塔里碱A(4)、塔里碱C(5)、塔里碱- v(6)、d-magnoflorine(7)、2-三甲基氨-3-（3-吲哚基）丙酸酯(8)、vakhmatine(9)和delatisine（10）。其中化合物1为新合成的lycoctonine型c19 -二萜生物碱，化合物4 ~ 10为首次从该植物中分离得到。
The present study was designed to determine the chemical constituents of Delphinium caeruleum Jacq. ex Camb.. The chemical constituents were isolated and purified by column chromatography with silica gel, ODS, and Sephadex LH-20. Their structures were elucidated by IR, MS, and NMR. Ten compounds were obtained and identified as caerudelphinine A (1), lycoctonine (2), talitine B (3), talitine A (4), talitine C (5), tatsienine-V (6), d-magnoflorine (7), 2-trimethyl-ammonio-3-(3-indolyl) propionate (8), vakhmatine (9), and delatisine (10). Compound 1 was a new lycoctonine-type C19-diterpenoid alkaloid, and compounds 4-10 were isolated from this plant for the first time.