INTRA-CORTICAL CONNECTIVITY OF ARCHITECTONIC FIELDS IN SOMATIC SENSORY, MOTOR AND PARIETAL CORTEX OF MONKEYS
INTRA-CORTICAL CONNECTIVITY OF ARCHITECTONIC FIELDS IN SOMATIC SENSORY, MOTOR AND PARIETAL CORTEX OF MONKEYS
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DOI：
10.1002/cne.901810206
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发表时间：
1978-01-01
影响因子：
2.5
通讯作者：
HENDRY, SHC
中科院分区：
文献类型：
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作者：
JONES, EG;COULTER, JD;HENDRY, SHC
采用顺行和逆行运输方法研究猴[猕猴和猕猴]大脑皮层3a、3b、1、2、5、4和6区域的皮质连通性。区域是通过同一大脑中的细胞结构特征和丘脑连接来识别的。通过首先记录短潜伏期组 I 传入诱发电位来识别区域 3a。尝试从以下方面分析数据：体感觉输入可能影响运动皮层神经元性能的途径；第一躯体感觉区（SI）的组成场中身体表面的可能多种表征。除了垂直层间连接外，还识别出两种类型的皮质内连接。第一种被认为是非特异性的，由轴突组成，轴突从同位素注射的各个侧面在 I、III 和 V-VI 层中展开；这些不加区别地跨越建筑边界。它们并不是所研究地区所独有的。第二种是由轴突进入白质并重新进入其他区域形成的。在这些中，它们终止于层 I-IV 中的 1 个或多个宽度相当恒定（0.5-1 毫米）的中间定向条带，并由类似尺寸的间隙分隔。然而，在区域 3b、区域 1 和 2（一起）、区域 3a 和 4（一起）以及区域 5 中隐含了单独的表示；在每种情况下，手指的表示都指向中央沟。区域 3b 不与区域 3a 或 4 连接，而是投影到组合区域 1 和 2。区域 1 与区域 3a 相互连接，区域 2 与区域 4 相互连接。按照惯例，区域 3a 的连通性最好不被视为一个实体，而最好被视为区域 4 的一部分。被其他人识别为区域 3a 的区域可能应被视为区域 3b 的一部分。区域 5 的部分应该更恰当地视为区域 2，以及不是从腹基底复合体而是从外侧核复合体和前丘脑接收丘脑输入的其他部分也与区域 4 互连。区域 5 的更多后部部分与区域 6 的侧向部分连接。区域 6 的更内侧部分，即辅助运动区，在感觉运动皮层中占据着关键位置，因为它 接收来自区域 3a、4、1、2 和 5（所有部分）的光纤，并投射回区域 3a、4 和 5。
Anterograde and retrograde transport methods were used to study the corticocortical connectivity of areas 3a, 3b, 1, 2, 5, 4 and 6 of the monkey [Macaca fascicularis and M. mulatta] cerebral cortex. Fields were identified by cytoarchitectonic features and by thalamic connectivity in the same brains. Area 3a was identified by first recording a short latency group I afferent evoked potential. Attempts were made to analyze the data in terms of: routes whereby somatic sensory input might influence the performance of motor cortex neurons; possible multiple representations of the body surface in the component fields of the 1st somatic sensory area (SI). Apart from vertical interlaminar connections, 2 types of intracortical connectivity are recognized. The first, regarded as non-specific, consists of axons spreading out in layers I, III and V-VI from all sides of an injection of isotope; these cross architectonic borders indiscrimininately. They are not unique to the regions studied. The second is formed by axons entering the white matter and re-entering other fields. In these, they terminate in layers I-IV in 1 or more mediolaterally orineted strips of fairly constant width (0.5-1 mm) and separated by gaps of comparable size. Separate representations are nevertheless implied in area 3b, in areas 1 and 2 (together), in areas 3a and 4 (together) and in area 5; with, in each case, the representations of the digits pointed at the central sulcus. Area 3b is not connected with areas 3a or 4, but projects to a combined areas 1 and 2. Area 1 is reciprocally connected with area 3a and area 2 reciprocally with area 4. The connectivity of area 3a, as conventionally identified, is such that is is probably best regarded not as an entity, but as a part of area 4. Areas identified by others as area 3a should probably be regarded as parts of area 3b. Parts of area 5 that should be more properly considered as area 2, and other parts that receive thalamic input not from the ventrobasal complex but from the lateral nuclear complex and anterior pulvinar, are also interconnected with area 4. More posterior parts of area 5 are connected with laterally placed parts of area 6. A more medial part of area 6, the supplementary motor area, occupies a pivotal position in the sensory-motor cortex, for it receives fibers from areas 3a, 4, 1, 2 and 5 (all parts), and projects back to areas 3a, 4 and 5.