Organic-base-catalyzed synthesis of phthalides via highly regioselective intramolecular cyclization reaction
Organic-base-catalyzed synthesis of phthalides via highly regioselective intramolecular cyclization reaction
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DOI：
10.1016/j.tetlet.2006.12.015
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发表时间：
2007-02-05
影响因子：
1.8
通讯作者：
Terada, Masahiro
中科院分区：
文献类型：
--
作者：
Kanazawa, Chikashi;Terada, Masahiro
有机碱催化邻炔基苯甲酸的5-外分子内环化反应区域选择性地以良好至优异的产率生成相应的苯酞。该方法提供了一个实用的方法来获得苯酞，一类重要的生物活性分子。(c)2006爱思唯尔有限公司版权所有。
The organic-base-catalyzed 5-exo intramolecular cyclization reaction of o-alkynylbenzoic acid produces the corresponding phthalide regioselectively in good to excellent yields. The method provides a practical access to the phthalides, an important class of biologically active molecules. (c) 2006 Elsevier Ltd. All rights reserved.