Eukaryotic Lsm proteins: lessons from bacteria.
Eukaryotic Lsm proteins: lessons from bacteria.
复制标题
真核 Lsm 蛋白：来自细菌的教训。
DOI：
10.1038/nsmb1037
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Wilusz,Jeffrey
中科院分区：
文献类型：
--
作者：
Wilusz,CarolJ;Wilusz,Jeffrey
Over the last five years Sm-like (Lsm) proteins have emerged as important players in many aspects of RNA metabolism, including splicing, nuclear RNA processing and messenger RNA decay. However, their precise function in these pathways remains somewhat obscure. In contrast, the role of the bacterial Lsm protein Hfq, which bears striking similarities in both structure and function to Lsm proteins, is much better characterized. In this perspective, we have highlighted several functions that Hfq shares with Lsm proteins and put forward hypotheses based on parallels between the two that might further the understanding of Lsm function.
