Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2)

Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2)
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DOI:
10.1016/j.pain.2009.02.007
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发表时间:
2009-07-01
期刊:
影响因子:
7.4
通讯作者:
Melzack, Ronald
Melzack, Ronald
中科院分区:
医学1区
文献类型:
--
作者:
Dworkin, Robert H.;Turk, Dennis C.;Melzack, Ronald

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本研究的目的是开发神经性和非神经性疼痛的主要症状的单一测量方法,可用于流行病学、自然病程、病理生理机制和治疗反应的研究。我们扩展和修订了简式麦吉尔疼痛问卷(1)(SF-MPQ)疼痛描述符,增加了与神经病理性疼痛相关的症状,并将响应格式修改为0-10数字分级标准,以在纵向研究和临床试验中提供更高的响应性。本研究以882例慢性疼痛综合征患者和226例糖尿病周围神经病变患者为研究对象,对修订后的SF-MPQ(SF-MPQ-2(1))的信度、效度和子量表结构进行了检验。这些数据表明,SF-MPQ-2具有良好的信度和效度,探索性和验证性因素分析的结果都支持四个易于解释的子量表--持续性疼痛、间歇性疼痛、以神经病理性疼痛为主的疼痛和情感描述。这些结果为SF-MPQ-2在未来的临床研究中的使用提供了基础,包括治疗神经病理性和非神经病理性疼痛的临床试验。(C)2009年国际疼痛研究协会。爱思唯尔出版,版权所有。
The objective of the present research was to develop a single measure of the major symptoms of both neuropathic and non-neuropathic pain that can be used in Studies of epidemiology, natural history, pathophysiologic mechanisms, and treatment response. We expanded and revised the Short-form McGill Pain Questionnaire(1) (SF-MPQ) pain descriptors by adding symptoms relevant to neuropathic pain and by modifying the response format to a 0-10 numerical rating scale to provide increased responsiveness in longitudinal studies and clinical trials. The reliability, validity, and subscale structure of the revised SF-MPQ (SF-MPQ-2(1)) were examined in responses from 882 individuals with diverse chronic pain syndromes and in 226 patients with painful diabetic peripheral neuropathy who participated in a randomized clinical trial. The data Suggest that the SF-MPQ-2 has excellent reliability and validity, and the results of both exploratory and Confirmatory factor analyses provided Support for four readily interpretable subscales-continuous pain, intermittent pain, predominantly neuropathic pain, and affective descriptors. These results provide a basis for use of the SF-MPQ-2 in future clinical research, including clinical trials of treatments for neuropathic and non-neuropathic pain conditions. (C) 2009 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.