Fish oil supplemental dose needed to reach 1 g% DHA + EPA in mature milk
Fish oil supplemental dose needed to reach 1 g% DHA + EPA in mature milk
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DOI：
10.1016/j.plefa.2017.11.003
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发表时间：
2018-01-01
影响因子：
3
通讯作者：
Muskiet, F. A. J.
中科院分区：
文献类型：
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作者：
Stoutjesdijk, E.;Schaafsma, A.;Muskiet, F. A. J.
简介：红细胞（RBC）DHA + EPA被认为是最佳的8 g%。终生高鱼摄入量的母亲表现出这种状态，产生的牛奶中含有约1g %的DHA + EPA。我们建立了将RBC DHA + EPA增加到8 g%和将牛奶DHA + EPA增加到1 g%所需的DHA + EPA补充剂量。225 + 90（n = 9）、450 + 180（n = 9）、675 + 270（n = 11）和900 + 360（n = 7）mg/天。结果：线性回归显示，所需剂量四舍五入为750 mg/天，以达到8 g% RBC DHA + EPA和1000 mg/天，以达到1 g%牛奶DHA+ EPA。RBC DHA + EPA增量取决于基线值。有没有影响牛奶AA，但牛奶EPA/AA ratio increased.Conclusion：妇女与RBC DHA + EPA状态的5.5克%需要750和1000毫克DHA + EPA/天，以达到8克% RBC DHA + EPA在妊娠结束时和1克%成熟的牛奶DHA + EPA，分别。
Introduction: Erythrocyte (RBC) DHA + EPA is considered optimal at 8 g%. Mothers with lifetime high fish intakes exhibiting this status produce milk with about 1 g% DHA + EPA. We established DHA + EPA supplemental dosages needed to augment RBC DHA + EPA to 8 g% and milk DHA + EPA to 1 g%.Materials and methods: Pregnant women were randomly allocated to DHA + EPA dosages of: 225 + 90 (n = 9), 450 + 180 (n = 9), 675 +270 (n = 11) and 900 + 360 (n = 7) mg/day. Samples were collected at 20 and 36 gestational weeks and 4 weeks postpartum.Results: Linear regression revealed needed dosages rounded at 750 mg/day to reach 8 g% RBC DHA + EPA and 1000 mg/day for 1 g% milk DHA+ EPA. RBC DHA + EPA increment depended on baseline values. There was no effect on milk AA, but milk EPA/AA ratio increased.Conclusion: Women with an RBC DHA + EPA status of 5.5 g% need 750 and 1000 mg DHA + EPA/day to reach 8 g% RBC DHA + EPA at the pregnancy end and 1 g% mature milk DHA + EPA, respectively.