Physical fitness and 4-year mortality in an 80-year-old population

Physical fitness and 4-year mortality in an 80-year-old population
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DOI:
10.1093/gerona/62.8.851
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发表时间:
2007-08-01
影响因子:
5.1
通讯作者:
Takehara, Tadamichi
Takehara, Tadamichi
中科院分区:
医学1区
文献类型:
--
作者:
Takata, Yutaka;Ansai, Toshihiro;Takehara, Tadamichi

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背景由于很少有人知道身体健康和死亡率之间的关系非常老年人,我们评估了这种关联在日本人口的80岁的社区居民。在日本福冈县的1282名80岁居民中,697人(277名男性和420名女性)进行了手握力、等长伸肌力量、等速伸肌力量、步速和单腿站立时间的体能测试。四年后,根据居民登记卡和官方死亡证明的数据,分析了这些年来参与者的死亡日期和原因。在4年的随访期间,107人(59名男性和49名女性)死亡。在这些死亡中,27人死于心血管疾病(CVD),27人死于癌症,22人死于肺炎,其余为其他原因。调整各种混杂因素后,全因死亡率的相对风险比(HR)随步进率的增加而下降。肺炎死亡率的HR随着腿部伸肌力量的增加而下降。相反,心血管疾病或癌症死亡率与身体健康之间没有关联。在80岁时身体健康受损与此后4年内死亡率增加之间存在部分关联。全因死亡率仅与踏步率相关,肺炎死亡率与伸腿肌力量相关。心血管疾病或癌症的死亡率与身体健康无关。
Background. Because little is known about the relationship between physical fitness and mortality among very elderly people, we evaluated this association in a Japanese population of 80-year-old community residents.Methods. Among 1282 80-year-old residents of Fukuoka Prefecture, Japan, 697 individuals (277 men and 420 women) underwent physical fitness tests of handgrip strength, isometric leg extensor strength, isokinetic leg extensor power, stepping rate, and one-leg standing time. Four years later, the dates and causes of death among the participants during those years were analyzed based on data from resident registration cards and from official death certificates.Results. During the 4-year follow-up period, 107 individuals (59 men and 49 women) died. Of these deaths, 27 were due to cardiovascular disease (CVD), 27 to cancer, 22 to pneumonia, and the rest to other causes. The relative hazard ratios (HR) for all-cause mortality, adjusted for various confounding factors, fell with increases in stepping rate. and the HR for pneumonia mortality fell with increases in leg extensor strength. In contrast, there was no association between cardiovascular or cancer mortality and physical fitness,Conclusions. A partial association was found between impaired physical fitness at the age of 80 years and increased mortality in the 4 years thereafter. Mortality due to all causes was related only to stepping rate, and mortality due to pneumonia was related to leg extensor strength. Mortality due to CVDs or cancers was not associated with physical fitness.