Levels of lipids, lipoproteins, and apolipoproteins in a defined population.
Levels of lipids, lipoproteins, and apolipoproteins in a defined population.
复制标题
特定人群中的脂质、脂蛋白和载脂蛋白水平。
DOI：
10.1016/s0025-6196(12)62470-7
复制
发表时间：
1991
影响因子：
8.9
通讯作者：
Weidman,WH
中科院分区：
文献类型：
--
作者：
Kottke,BA;Moll,PP;Michels,VV;Weidman,WH
As part of a large cross-sectional investigation—the Rochester Family Heart Study—plasma levels of lipids, lipoproteins, and apolipoproteins were measured in a sample from the general population of male and female subjects who ranged in age from 5 to 90 years. Polyclonal radioimmunoassays developed at the Mayo Clinic were used for measurement of apolipoproteins A-I, A-II, C-II, C-III, and E, whereas a monoclonal enzyme-linked immunosorbent assay was used for apolipoprotein B. On the basis of 984 subjects who reported that they were fasting, were not pregnant, had never smoked, and were taking no medications thought to influence lipid levels, we determined age- and gender-specific percentiles for plasma levels of cholesterol, triglycerides, high-density lipoprotein cholesterol, and six apolipoproteins. These percentiles will facilitate identification of persons who are in the highest and lowest percentiles for their age and gender. The levels of the apolipoproteins varied for both age and gender. This is the first study to provide a reference sample for plasma levels of these apolipoproteins for male and female subjects 5 to 90 years of age selected from the general population.
