Repetitive and stereotyped movements in children with autism spectrum disorders late in the second year of life

Repetitive and stereotyped movements in children with autism spectrum disorders late in the second year of life
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DOI:
10.1111/j.1469-7610.2008.01904.x
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发表时间:
2008-08-01
影响因子:
7.6
通讯作者:
Barber, Angie
Barber, Angie
中科院分区:
医学1区
文献类型:
--
作者:
Morgan, Lindee;Wetherby, Amy M.;Barber, Angie

文献摘要

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目的:本研究的目的是使用一种新的临床工具来测量幼儿的重复和刻板动作(RSM),以检查组间差异及其与后期发育水平和自闭症症状的关系。方法:对18 - 24月龄的自闭症谱系障碍(ASD, n = 50)、非ASD发育迟缓(DD, n = 25)和典型发育(TD, n = 50)儿童,采用交流与符号行为量表(CSBS, Wetherby & Prizant, 2002)进行录像行为样本编码。结果:在系统行为样本中,ASD患儿与DD组和TD组相比,表现出更高的物体和身体的RSM发生率和更大的库存。RSM的测量与ASD组第四年的社会沟通和预测发育结果和自闭症症状的同步测量有关。在控制CSBS符号水平时,RSM与自闭症症状之间的相关性均不显著。有物体的RSM预测了第四年自闭症症状严重程度的独特差异,超出了单独使用社会沟通测量的预测。结论:本研究支持了RSM在24个月以下儿童中的诊断意义,并证明了RSM测量工具作为CSBS的配套工具的实用性。
Objectives: The purpose of this study was to examine group differences and relationships with later developmental level and autism symptoms using a new clinical tool developed to measure repetitive and stereotyped movements (RSM) in young children. Method: Videotaped behavior samples using the Communication and Symbolic Behavior Scales Developmental Profile (CSBS; Wetherby & Prizant, 2002) were coded for children with autism spectrum disorders (ASD; n = 50), developmental delays without ASD (DD; n = 25), and typical development (TD; n = 50) between 18 and 24 months of age. Results: Children with ASD demonstrated significantly higher rate and larger inventory of RSM with objects and body during a systematic behavior sample than both the DD and TD groups. Measures of RSM were related to concurrent measures of social communication and predicted developmental outcomes and autism symptoms in the fourth year for the ASD group. None of the correlations between RSM and autism symptoms remained significant when controlling for CSBS Symbolic level. RSM with objects predicted unique variance in the severity of autism symptoms in the fourth year beyond that predicted by social communication measures alone. Conclusions: This study provides support for the diagnostic significance of RSM in children under 24 months of age and documents the utility of this RSM measurement tool as a companion to the CSBS.