A new phenolic metabolite, involutone, isolated from the mushroom Paxillus involutus
A new phenolic metabolite, involutone, isolated from the mushroom Paxillus involutus
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DOI：
10.1139/v02-194
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发表时间：
2003-01-01
影响因子：
1.1
通讯作者：
Mikolajczyk, L
中科院分区：
文献类型：
--
作者：
Antkowiak, R;Antkowiak, WZ;Mikolajczyk, L
在新鲜采集的卷曲霉菌的甲醇、乙醇或正丁醇提取物中发现了一种新的光学活性代谢物--卷曲内酯。根据对开内酯及其四乙酰衍生物的光谱和化学性质，证明该化合物为5-(3，4-dihydroxyphenyl)-2-(4-hydroxyphenyl)-2-hydroxy-4-cyclopenten-1，3-dione结构。此外，一些已知结构的化合物，如亚油酸和巴豆酸、甘露醇、麦角甾醇、内含素，以及甲基、乙基或正丁基-β-D-葡萄糖苷，以及甲基、乙基或正丁基亚油酸甲酯、乙基或正丁基亚油酸酯，也以纯状态从蘑菇中分离出来。
A new optically active metabolite, involutone, was found in methanol, ethanol, or n-butanol extracts of freshly collected Paxillus involutus. The structure of this compound was proved to be 5-(3,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)-2-hydroxy-4-cyclopenten-1,3-dione on the basis of the spectral and chemical properties of involutone and its tetraacetyl derivative. In addition, a number of compounds of known structures such as linoleic and crotonic acids, mannitol, ergosterol, involutin, as well as methyl, ethyl, or n-butyl-beta-D-glucopyranosides, and methyl, ethyl, or n-butyl linoleates, depending in both cases on the alcohol used in the extraction, were also isolated in a pure state from the mushroom.