Pesticide exposure and risk of mild cognitive dysfunction
Pesticide exposure and risk of mild cognitive dysfunction
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DOI：
10.1016/s0140-6736(00)02685-4
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发表时间：
2000-09-09
期刊：
影响因子：
168.9
通讯作者：
Jolles, J
中科院分区：
文献类型：
--
作者：
Bosma, H;van Boxtel, MPJ;Jolles, J
人们对杀虫剂和金属等物质对轻度认知功能障碍 (MCD) 的不利影响知之甚少。马斯特里赫特衰老研究的横截面和前瞻性数据被用来找出特定物质的潜在神经毒性。接触杀虫剂（例如耕种的农民和园丁）与 MCD 风险增加有关。接触金属和有机溶剂与 MCD 无关。我们的发现可能反映了接触农药的人大脑功能的微妙变化。
Little Is known about the adverse effects of substances, such as pesticides and metals, on the development of mild cognitive dysfunction (MCD). Cross-sectional and prospective data from the Maastricht Aging Study were used to find out the potential neurotoxicity of particular substances. Exposure to pesticides, for example by arable farmers and gardeners, was associated with increased risks of MCD. Exposure to metals and organic solvents was not associated with MCD. Our findings might reflect subtle changes in brain function among people exposed to pesticides.