Prognosis of cancers associated with venous thromboembolism.
Prognosis of cancers associated with venous thromboembolism.
复制标题
DOI：
10.1056/nejm200012213432504
复制
发表时间：
2000-12-21
影响因子：
158.5
通讯作者：
Baron, JA
中科院分区：
文献类型：
--
作者：
Sorensen, HT;Mellemkjær, L;Baron, JA
背景资料：鲜为人知的是，发现在一段时间或之后的Venous thromboembolism.Methods的癌症预后：我们联系了丹麦国家登记处的患者，丹麦癌症登记处，和丹麦死亡率档案，以获得数据的生存期的患者谁收到了诊断为癌症的同时或之后的一段时间的Venous thromboembolism。他们的生存率与没有静脉血栓栓塞的癌症患者进行了比较（对照组），在癌症类型、年龄、性别和诊断年份方面相匹配。在668名发生深静脉血栓栓塞时患有癌症的患者中，44.0%的患者有疾病扩散的数据，563例患者有远处转移，而5371例有扩散数据的对照患者中有35.1%有远处转移（患病率为1.26; 95%可信区间为1.13 ~ 1.40）。在静脉血栓栓塞时患有癌症的一组中，一年生存率为12%，而对照组为36%（P
Background: Little is known about the prognosis of cancer discovered during or after an episode of venous thromboembolism.Methods: We linked the Danish National Registry of Patients, the Danish Cancer Registry, and the Danish Mortality Files to obtain data on the survival of patients who received a diagnosis of cancer at the same time as or after an episode of venous thromboembolism. Their survival was compared with that of patients with cancer who did not have venous thromboembolism (control patients), who were matched in terms of type of cancer, age, sex, and year of diagnosis.Results: Of 668 patients who had cancer at the time of an episode of deep venous thromboembolism, 44.0 percent of those with data on the spread of disease (563 patients) had distant metastasis, as compared with 35.1 percent of 5371 control patients with data on spread (prevalence ratio, 1.26; 95 percent confidence interval, 1.13 to 1.40). In the group with cancer at the time of venous thromboembolism, the one-year survival rate was 12 percent, as compared with 36 percent in the control group (P