Organohalogen compounds and their metabolites in the blood of Japanese amberjack (Seriola quinqueradiata) and scalloped hammerhead shark (Sphyrna lewini) from Japanese coastal waters
Organohalogen compounds and their metabolites in the blood of Japanese amberjack (Seriola quinqueradiata) and scalloped hammerhead shark (Sphyrna lewini) from Japanese coastal waters
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DOI：
10.1016/j.chemosphere.2011.06.092
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发表时间：
2011-10-01
期刊：
影响因子：
8.8
通讯作者：
Tanabe, Shinsuke
中科院分区：
文献类型：
--
作者：
Nomiyama, Kei;Uchiyama, Yukiko;Tanabe, Shinsuke
关于海洋鱼类血液中多氯联苯代谢物（OH-PCBs）和羟基化多溴联苯醚（OH-PBDEs）积累的信息有限。本研究以日本沃茨的双髻鲨（Sphyrna lewini）和日本琥珀鱼（Seriola quinqueradiata）为研究对象，测定了其血液中PCBs、OH-PCBs、PBDEs、OH-PBDEs和甲氧基化PBDEs（MeO-PBDEs）的残留水平和分布规律。在日本琥珀鱼体内发现的主要同系物是单氯和二氯羟基多氯联苯，而双髻鲨体内发现的同系物是八氯羟基多氯联苯。日本琥珀中主要的OH-PCB异构体是低氯化的OH-PCB，如6 OH-CB 2和2 'OH-CB 9。这一结果表明，日本琥珀暴露于低氯化羟基多氯联苯可能是从周围的水生环境。在双髻鲨中，4，4 'diOH-CB 202、4 OH-CB 201和4 OH-CB 146是主要的异构体，约占OH-PCB总量的60%。至于羟基-多溴二苯醚异构体，在日本琥珀鱼和双髻鲨中，主要是6-羟基-BDE 47，其次是2 '-羟基-BDE 68。Sigma MeO-PBDEs和Sigma OH-PBDEs的残留水平呈显著正相关（p = 0.029）。这一结果表明，MeO-PBDEs和OH-PBDEs在鱼类体内有着共同的来源或代谢途径。在日本琥珀鱼和双髻鲨体内发现的羟基多氯联苯和羟基多溴二苯醚特征差异表明，需要进一步研究鱼类接触特征、代谢能力和毒性效应的差异。(C)2011爱思唯尔有限公司保留所有权利。
Information on accumulation of polychlorinated biphenyl metabolites (OH-PCBs) and hydroxylated polybrominated diphenyl ethers (OH-PBDEs) in the blood of marine fish is limited. The present study, we determined the residue levels and patterns of PCBs, OH-PCBs, PBDEs, OH-PBDEs and methoxylated PBDEs (MeO-PBDEs) in the blood collected from scalloped hammerhead shark (Sphyrna lewini) and Japanese amberjack (Seriola quinqueradiata), species of predatory fish at Japanese coastal waters. The predominant homologues found in Japanese amberjacks were mono- and di-chlorinated OH-PCBs, and scalloped hammerhead sharks were octa-chlorinated OH-PCBs. The predominant OH-PCB isomers were lower-chlorinated OH-PCBs such as 6OH-CB2 and 2'OH-CB9 in Japanese amberjacks. This result suggests that exposure of Japanese amberjacks to lower-chlorinated OH-PCBs might be from the ambient aquatic environment. In scalloped hammerhead sharks, 4,4'diOH-CB202, 4OH-CB201 and 4OH-CB146 were the predominant isomers accounting for approximately 60% of the total OH-PCBs.The predominant MeO-PBDE isomers were 6MeO-BDE47 followed by 2'MeO-BDE68 in both species. As for OH-PBDE isomers, 6OH-BDE47 was predominant followed by 2'OH-BDE68 in Japanese amberjacks and scalloped hammerhead sharks. Residue levels of Sigma MeO-PBDEs and Sigma OH-PBDEs showed a significant positive correlation (p = 0.029). This result suggests that MeO-PBDEs and OH-PBDEs share a common source or a metabolic pathway in fishes. Characteristic differences found in the profiles of OH-PCBs and OH-PBDEs in Japanese amberjack and scalloped hammerhead shark show the need for further studies on the differences in exposure profiles, metabolic capacities and toxic effects in fish. (C) 2011 Elsevier Ltd. All rights reserved.