Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: a randomized controlled trial
Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: a randomized controlled trial
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DOI：
10.1016/j.ajog.2016.10.019
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发表时间：
2017-02-01
影响因子：
9.8
通讯作者：
Sanci, Muzaffer
中科院分区：
文献类型：
--
作者：
Gungorduk, Kemal;Ozdemir, Aykut;Sanci, Muzaffer
背景：选择性手术后发生的麻痹性肠梗阻是一种常见且不舒服的并发症，被认为是腹腔手术后不可避免的。目的：本研究的目的是研究咖啡是否能加速妇科癌症完全分期手术后肠功能的恢复。研究设计：在这项随机对照试验中，114名患者术前被分配到术后每天喝3次咖啡（n 58）或术后不喝咖啡的常规护理（n 56）。作为子宫内膜癌、卵巢癌、子宫癌或输卵管癌分期手术的一部分，所有患者均行全腹子宫切除术和双侧输卵管卵巢切除术并行系统盆腔和主动脉旁淋巴结切除术。主要观察指标是术后到首次排气的时间。次要结果是第一次排便的时间，第一次排便的时间，以及对固体饮食的耐受时间。结果：平均排气时间（30.2 +/- 8.0 vs 40.2 +/- 12.1 h）
BACKGROUND: Paralytic ileus that develops after elective surgery is a common and uncomfortable complication and is considered inevitable after an intraperitoneal operation.OBJECTIVE: The purpose of this study was to investigate whether coffee consumption accelerates the recovery of bowel function after complete staging surgery of gynecologic cancers. STUDYDESIGN: In this randomized controlled trial, 114 patients were allocated preoperatively to either postoperative coffee consumption with 3 times daily (n 58) or routine postoperative care without coffee consumption (n 56). Total abdominal hysterectomy and bilateral salpingooophorectomy with systematic pelvic and paraaortic lymphadenectomy were performed on all patients as part of complete staging surgery for endometrial, ovarian, cervical, or tubal cancer. The primary outcome measure was the time to the first passage of flatus after surgery. Secondary outcomes were the time to first defecation, time to first bowel movement, and time to tolerance of a solid diet.RESULTS: The mean time to flatus (30.2 +/- 8.0 vs 40.2 +/- 12.1 hours; P