Fasting and postprandial soluble epoxide hydrolase-associated eicosanoids of remitted patients with eating disorder.
Fasting and postprandial soluble epoxide hydrolase-associated eicosanoids of remitted patients with eating disorder.
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DOI：
10.1016/j.dib.2018.01.028
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发表时间：
2018-04
期刊：
影响因子：
1.2
通讯作者：
Shih PB
中科院分区：
文献类型：
--
作者：
Yang J;Shih PB
食物厌恶和食物回避是神经性厌食症等进食障碍患者需要克服的重大挑战。环氧化物水解酶2基因（EPXH2）是一种新的神经性厌食症危险基因。我们还发现EPHX 2相关的类花生酸衍生自多不饱和脂肪酸是异常的神经性厌食症患者，这表明遗传调节的脂质代谢可能是AN发病机制的一个潜在因素。本文中提供的数据与题为“个性化多不饱和脂肪酸作为神经性厌食症的潜在预防性治疗”的研究文章相关。在这篇数据文章中，我们提供了进食障碍缓解患者和健康对照者的空腹和非空腹（餐后）类花生酸浓度。这些数据提供了有关禁食和非禁食状态下定量生物活性脂质介质的信息，从而可以推断与食物消耗相关的脂质代谢。该数据集可用于进行关键或扩展分析。
Food aversion and food avoidance are significant challenges to overcome for patients with eating disorder such as anorexia nervosa. The epoxide hydrolase 2 gene (EPXH2) has been uncovered as a novel anorexia nervosa risk gene. We have also discovered EPHX2-associated eicosanoids derived from polyunsaturated fatty acids to be aberrant in patients with anorexia nervosa, suggesting that genetically moderated lipid metabolism may be an underlying factor in AN pathogenesis. The data presented in this article are related to the research article entitled “Personalized polyunsaturated fatty acids as a potential adjunctive treatment for anorexia nervosa”. In this data article, we provide both fasting and non-fasting (postprandial) concentration of eicosanoids in remitted patients with eating disorder and healthy controls. The data provides information on quantitative bioactive lipid mediators in fasting as well as non-fasting states, allowing inference of lipid metabolism associated with food consumption. The data set is made available to enable critical or extended analyzes.