Psychopathology and achievement in children at high risk for developing alcoholism

Psychopathology and achievement in children at high risk for developing alcoholism
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DOI:
10.1097/00004583-199907000-00019
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发表时间:
1999-07-01
影响因子:
13.3
通讯作者:
Connolly, J
Connolly, J
中科院分区:
医学1区
文献类型:
--
作者:
Hill, SY;Locke, J;Connolly, J

文献摘要

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目的:比较酒精中毒高风险或低风险儿童的精神病理学和学业成绩的发生率,并确定学业缺陷是否可以预测未来一年内发生的精神病理学。方法:作为纵向随访的一部分,对8至18岁的儿童和青少年进行了评价。通过使用学龄儿童情感障碍和精神分裂症量表获得的诊断以及广泛成就测试的阅读、拼写和算术部分的年级等效分数每年确定一次。结果:高风险的后代更有可能患有可诊断的疾病。此外,使用母亲和父亲的酒精中毒诊断作为协变量的分析显示,选定的障碍(抑郁症,情感障碍,注意力缺陷/多动障碍和行为障碍)的风险比更高,其中一些是性别依赖的。逻辑回归分析的成绩测试成绩表明,阅读和数学成绩预测存在的儿童精神病理学在以下年度评估。结论:来自高密度酗酒家系的儿童患精神病理学的风险更大,此外,观察到的学习成绩缺陷可能被认为是发展中的可诊断疾病的指标。
Objective: To compare rates of psychopathology and academic achievement in children who were either at high or low risk for developing alcoholism and to determine whether academic deficits would predict prospectively the presence of psychopathology occurring within the next year. Method: Children and adolescents, aged 8 to 18 years, were evaluated as part of a longitudinal follow-up. Diagnoses obtained by using the Schedule for Affective Disorders and Schizophrenia for School-Age Children and grade-equivalent scores from the reading, spelling, and arithmetic sections of the Wide Range Achievement Test were determined at yearly intervals. Results: High-risk off spring were more likely to have a diagnosable disorder. In addition, analyses using the mother's and father's diagnosis of alcoholism as a covariate showed higher hazard ratios for selected disorders (depression, affective disorder, attention-deficit/hyperactivity disorder, and conduct disorder), some of which were gender-dependent. Logistic regression analysis of achievement test scores demonstrated that reading and math scores predicted the presence of childhood psychopathology at the following annual evaluation. Conclusions: Children from pedigrees with a high density of alcoholism are at greater risk for developing psychopathology, Furthermore, observed deficits in academic performance may be considered an indicator of a developing diagnosable illness.