Progress Report on the Generation of Polyfunctional Microscale Particles for Programmed Self-Assembly.
Progress Report on the Generation of Polyfunctional Microscale Particles for Programmed Self-Assembly.
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用于程序化自组装的多官能微米级粒子的生成进展报告。
DOI：
10.1021/cm403637v
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Willson,CGrant
中科院分区：
文献类型：
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作者：
Deschner,Ryan;Tang,Hao;Allen,Peter;Hall,Cecilia;Hlis,Rocco;Ellington,Andrew;Willson,CGrant
描述了一种使用ssDNA杂交作为缔合力的可平版印刷的微米级聚合物颗粒的3D编程自组装的方法。我们报告了我们在建立3D程序化自组装所需的单元过程方面的进展，并证明了共价ssDNA功能化平行六面体的成功制造和序列特异性自组装，其尺寸在10 μm以下，通过光学显微镜和成像流式细胞术表征。该技术有可能产生每个面上具有不同ssDNA的平行六面体颗粒。
A process for 3D programmed self-assembly of lithographically printable microscale polymer particles using ssDNA hybridization as the associative force is described. We report our progress in establishing the unit processes required for 3D programmed self-assembly and demonstrate the successful fabrication and sequence-specific self-assembly of covalent ssDNA-functionalized parallelepipeds with dimensions in the sub 10 μm regime characterized by optical microscopy and imaging flow cytometry. This technology has the potential to produce parallelepiped particles with different ssDNA on each facet.