Palladium-catalyzed regio- and diastereoselective allylic alkylation with azlactones using triphenylarsine
Palladium-catalyzed regio- and diastereoselective allylic alkylation with azlactones using triphenylarsine
复制标题
DOI：
10.1055/s-2006-950400
复制
发表时间：
2006-09-18
期刊：
影响因子：
2
通讯作者：
Uenishi, Junichi
中科院分区：
文献类型：
--
作者：
Kawatsura, Motoi;Ikeda, Daiji;Uenishi, Junichi
成功地实现了钯催化的(R)-2-乙酰氧基-4-苯基-3-丁烯与氮内酯的区域和非对映选择性的烷基化反应。立体化学受到高度控制，反应生成了具有邻位手性季碳中心和叔碳中心的偶联产物。
The palladium-catalyzed regio- and diastereoselective allylic alkylation of (R)-2-acetoxy-4-phenyl-3-butene with azlactones using AsPh3 successfully occurred. The stereochemistries were highly controlled, and the reaction produced a coupling product which possessed vicinal chiral quaternary and tertiary carbon centers.