SOMATOSENSORY AFFERENTS IN THE PARASYMPATHETIC VASODILATOR REFLEX IN CAT LIP
SOMATOSENSORY AFFERENTS IN THE PARASYMPATHETIC VASODILATOR REFLEX IN CAT LIP
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DOI：
10.1016/0165-1838(92)90016-a
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发表时间：
1992-07-01
期刊：
影响因子：
--
通讯作者：
IZUMI, H
中科院分区：
文献类型：
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作者：
KARITA, K;IZUMI, H
本文研究了猫口面部伤害感受器激活引起的躯体-副交感神经反射性血管舒张。在戊巴比妥麻醉和人工呼吸猫下唇血流量的变化进行了监测激光多普勒流量计。捏和热刺激的口面区域诱发的血流量增加类似于电诱导血管舒张。当将1%的辣椒素溶液施加到舌头上时，获得了血流的持续增加的反应。这些结果表明，C-多模态伤害感受器是一个强有力的候选人的受体，挑起躯体副交感神经血管舒张。然而，辣椒素不敏感的神经纤维也参与其中，因为辣椒素处理过的舌头的电刺激引起血管舒张。伤害性刺激引起的血管舒张和全身血压变化之间的相关性也进行了讨论。
Somato-parasympathetic reflexive vasodilatation elicited by activation Of the nociceptors in the oro-facial areas of the cat was investigated. Changes in lower lip blood flow monitored by a laser Doppler flowmeter took place in pentobarbital-anesthetized and artificially respirated cats. Pinch and heat stimulation of the oro-facial areas evoked a blood flow increase similar to that of electrically induced vasodilatation. Sustained increased responses in blood flow were obtained when a 1 % capsaicin solution was applied to the tongue. These results show that the C-polymodal nociceptor is a strong candidate for a receptor that provokes somato-parasympathetic vasodilatation. Capsaicin-insensitive nerve fibers, however, also participate because electrical stimulation of the capsaicin-treated tongue evoked vasodilatation. The correlation between noxious stimulation-induced vasodilatation and systemic blood pressure change also is discussed.